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3 Polish Journal of Chemistry

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Butyrylcholinesterase Inhibitory C-Glycoside from Symplocos racemosa

Ahmad V., Zubair M., Abbasi M., Kousar F., Rasheed M., Rasool N., Hussain J., Nawaz S., Choudhary M.

Polish Journal of Chemistry

2006

Vol. 80, nr 3

403-407

The re-investigation of the chemical constituents of Symplocos racemosa Roxb. led to the isolation of one new C-glycoside, symcososide (1) along with one known compound beta-sito-glycoside (2). The structure of the new compound was determined by 1D and 2Dhomonuclear and heteronuclearNMRspectroscopy, chemical evidences, and by comparison with the published data of the closely related compounds. The glycoside 1 displayed in vitro inhibitory activity against butyrylcholinesterase (BChE) enzyme with IC50 value of 21.2 š 0.01 miM.

Antioxidant Flavonoids from Pulicaria undulata

Ahmad V., Rasool N., Abbasi M., Rashid M., Kousar F., Zubair M., Ejaz A., Choudhary M., Tareen R.

Polish Journal of Chemistry

2006

Vol. 80, nr 5

745-751

The phytochemical investigation of the ethyl acetate soluble fraction of the whole plant of Pulicaria undulata L. (syn. Pulicaria crispa Forssk.) yielded two new flavonoid glycosides, pulicaroside (1) and undulatoside (6) along with four known flavonones (2-5). The structures of the new compounds were identified by 1D and 2D-NMR techniques along with other spectral evidences and by the comparison with the published data of the closely related compounds. All the flavonoids (1-6) exhibited superoxide anion scavenging activity.

Limbatolide F and G: Two New trans-Clerodane Diterpenoids from Otostegia limbata

Farooq U., Khan A., Ahmad V., Kousar F., Iqbal S.

Polish Journal of Chemistry

2005

Vol. 79 / nr 11

1757-1762

Two new trans-clerodane diterpenoids pro vi sion ally named as limbatolide F (1) and limbatolide G (2) were isolated from the chloroform extract of Otostegia limbata. Both compounds 1 and 2 have a unique feature of C-4/C-6 five membered a,b-un saturated lactone. The structures of these new compounds as well as their relative configurations were determined by 1D and 2D NMR techniques including COSY, HMQC, HMBC, NOESY and NOE experiments.