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Laser generated gold nanoparticles for mass spectrometry of low molecular weight compounds

Płaza-Altamer Aneta, Kołodziej Artur, Nizioł Joanna, Ruman Tomasz

Chemical Technology & Biotechnology

2022

Vol. 3

61--69

Preparation of gold nanoparticles (AuNPs) by pulsed fiber laser (PFL) laser generated nanomaterial (LGN) with the use of 2D galvo-scanner (2D GS) is described. The procedure of covering of custom-made stainless steel MALDI targets containing studied objects via nebulization is also presented. Examples of application of new method (PFL-2D GS LGN and nebulization) in laser desorption/ionization mass spectrometry (LDI MS) analyses are shown. These include tests with amino acids and also low molecular weight polymer.