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Content available remote Tissue P Systems with Small Cell Volume
EN
Traditionally, P systems allow their membranes or cells to grow exponentially (or even more) in volume with respect to the size of the multiset of objects they contain in the initial configuration. This behaviour is, in general, biologically unrealistic, since large cells tend to divide in order to maintain a suitably large surface-area-to-volume ratio. On the other hand, it is usually the number of cells that needs to grow exponentially with time by binary division in order to solve NP-complete problems in polynomial time. In this paper we investigate families of tissue P systems with cell division where each cell has a small volume (i.e., sub-polynomial with respect to the input size), assuming that each bit of information contained in the cell, including both those needed to represent the multiset of objects and the cell label, occupies a unit of volume. We show that even a constant volume bound allows us to reach computational universality for families of tissue P systems with cell division, if we employ an exponential-time uniformity condition on the families. Furthermore, we also show that a sub-polynomial volume does not suffice to solve NP-complete problems in polynomial time, unless the satisfiability problem for Boolean formulae can be solved in sub-exponential time, and that solving an NP-complete problem in polynomial time with logarithmic cell volume implies P = NP.
2
Content available remote Efficient Simulation of Reaction Systems on Graphics Processing Units
EN
Reaction systems represent a theoretical framework based on the regulation mechanisms of facilitation and inhibition of biochemical reactions. The dynamic process defined by a reaction system is typically derived by hand, starting from the set of reactions and a given context sequence. However, this procedure may be error-prone and time-consuming, especially when the size of the reaction system increases. Here we present HERESY, a simulator of reaction systems accelerated on Graphics Processing Units (GPUs). HERESY is based on a fine-grained parallelization strategy, whereby all reactions are simultaneously executed on the GPU, therefore reducing the overall running time of the simulation. HERESY is particularly advantageous for the simulation of large-scale reaction systems, consisting of hundreds or thousands of reactions. By considering as test case some reaction systems with an increasing number of reactions and entities, as well as an increasing number of entities per reaction, we show that HERESY allows up to 29× speed-up with respect to a CPU-based simulator of reaction systems. Finally, we provide some directions for the optimization of HERESY, considering minimal reaction systems in normal form.
3
Content available remote Membrane Division, Oracles, and the Counting Hierarchy
EN
Polynomial-time P systems with active membranes characterise PSPACE by exploiting membranes nested to a polynomial depth, which may be subject to membrane division rules. When only elementary (leaf) membrane division rules are allowed, the computing power decreases to PPP = P#P, the class of problems solvable in polynomial time by deterministic Turingmachines equipped with oracles for counting (or majority) problems. In this paper we investigate a variant of intermediate power, limiting membrane nesting (hence membrane division) to constant depth, and we prove that the resulting P systems can solve all problems in the counting hierarchy CH, which is located between PPP and PSPACE. In particular, for each integer k ≥ 0 we provide a lower bound to the computing power of P systems of depth k.
4
Content available remote Constant-Space P Systems with Active Membranes
EN
We show that a constant amount of space is sufficient to simulate a polynomial-space bounded Turing machine by P systems with active membranes. We thus obtain a new characterisation of PSPACE, which raises interesting questions about the definition of space complexity for P systems. We then propose an alternative definition, where the size of the alphabet and the number of membrane labels of each P system are also taken into account. Finally we prove that, when less than a logarithmic number of membrane labels is available, moving the input objects around the membrane structure without rewriting them is not enough to even distinguish inputs of the same length.
5
Content available remote Computing Issues of Asynchronous CA
EN
This work studies some aspects of the computational power of fully asynchronous cellular automata (ACA). We deal with some notions of simulation between ACA and Turing Machines. In particular, we characterize the updating sequences specifying which are “universal”, i.e., allowing a (specific family of) ACA to simulate any Turing machine on any input. We also consider the computational cost of such simulations. Finally, we deal with ACA equipped with peculiar updating sequences, namely those generated by random walks.
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