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Material characteristic of an innovative stent for the treatment of urethral stenosis

Kurowiak Jagoda, Mackiewicz Agnieszka, Klekiel Tomasz, Będziński Romuald

Acta Mechanica et Automatica

2023

Vol. 17, no. 3

477--484

The appropriate development and customisation of the stent to the urethral tissues requires the determination of many factors such as strength and degradation. Given the distinctive conditions of urethral tissues, it is important that the design of the stent be properly developed. The selection of a stent material requires knowing its material characteristics and verifying that they are suitable for the future implantation site. In the present study, the development of a polydioxanone (PDO)-based stent was undertaken. The PDO material was fabricated using an additive technique – 3D printing. Then, in vitro tests were performed to determine the degradation time of the material under conditions simulating an aggressive urinary environment. The changes in the parameters of mechanical properties before and after the degradation period were determined, and the changes in the structure of the material before and after degradation were observed. Numerical analysis was performed for the proposed stent design. The results showed that PDO has good mechanical properties, but its degradation time is too short to be used in a urethral stent. Among the innovations of the studies conducted are bending strength tests, which is not a frequently considered aspect so far.

Badania biomechaniczne tchawicy w warunkach wielokierunkowego obciążenia

Maksymczak Natalia, Dudek Arkadiusz, Noszczyk-Nowak Agnieszka, Mackiewicz Agnieszka, Będziński Romuald

Aktualne Problemy Biomechaniki

2019

z. 17

51--57

Uszkodzenia tchawicy spowodowane wprowadzeniem rur umożliwiających przywrócenie wentylacji płuc. Identyfikacja parametrów mechanicznych jest konieczna w celu rozpoznania patomechanizmu zmian w tkance, związanych z nieprawidłową przebudową. Uzyskane rezultaty badań mechanicznych pozwoliły na opracowanie modelu matematycznego tchawicy w warunkach wielokierunkowego obciążenia. Umożliwi to przewidywanie nadmiernych lokalnych zaburzeń pól odkształceń i naprężeń tchawicy, występujących podczas wprowadzenia rurki intubacyjnej, które do tej pory nie zostały jeszcze dokładnie zbadane.

Tracheal injury caused by the introduction of tubes to restore lung ventilation. Identification of mechanical parameters is necessary in order to identify changes in the pathomechanism of tissue associated with abnormal remodeling. The results of mechanical tests allowed us to develop a mathematical model of the trachea in a multidirectional load conditions. This will allow prediction of excessive local disturbances of the fields of strain and stress in the trachea wall occurring during the insertion of the tracheal tube, which so far have not yet been thoroughly investigated.