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EN
The aim of the present study was to test if the exposure to transcranial direct current stimulation (tDCS) would change the excitability of the visual cortex and influence an accommodative response of the ocular lens. Twenty four subjects were divided into two groups: real-stimulation of the occipital cortex in which participants were exposed to real stimulation (1 mA for 12 min), and sham in which subjects were tested with placebo stimulation. The results showed that tDCS might indeed influence accommodative response. The strongest and most evident effect was observed when a 3.0 D accommodative stimulus was used: anodal tDCS increased but cathodal tDCS – decreased the accommodative response. The second finding was that the effect of stimulation was dependent on the examined eye. The right eye with slightly lower visual acuity and weaker accommodative response in pre-test, responded more strongly than the left eye. The short-time tDCS might modulate excitability of the neurons in visual cortex and eye sensitivity, reflected in the change of accommodative response. The tDCS method may be considered a technique that could reinforce conventional active visual training to improve accommodative functions.
EN
The paper presents results of spectral and photophysical studies obtained for molecules representing three different classes of compounds: • Schiff bases with strong intramolecular hydrogen bond, occurring in a few phototautomers, • Aminophtalimides with LE and ICT type electronic excited states forming exciplexes through hydrogen bonds with the solvent molecules, • Thioketones with a thiocarbonyl group becoming exceptionally reactive in the S2 state, quenched by molecules of solvent of different properties. It should be emphasized that for all compounds, irrespective of the complex mechanisms of their deactivation characterised by different dynamics, the dominant final process is the reproduction of the chemically unchanged substrate in the ground state. The necessary condition of the correct interpretation of the complex properties of the compounds studied in electronic excited states is the proper choice of solvents of specific properties. Through this proper choice of solvents it becomes possible to study the role of nonspecific and specific (hydrogen bonds) interactions with the solvent and to observe the intramolecular and intermolecular processes of deactivation. The results presented could be obtained thanks to the use of the steady-state and time-resolved laser methods of absorption and emission spectroscopy with a pico- and femtosecond resolution. The results obtained can be helpful in the study of compounds of similar properties and more complex systems including biological systems.
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