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Visible Human Projects - a step towards the virtual patient: models and simulations

Król Z., Chlebiej M., Mikołajczak P., Hoffmann K.-H.

Journal of Medical Informatics & Technologies

2004

Vol. 7

MIP51--58

This paper reports on our experiences using datasets from the Visible Human Project in different biomedical applications. Introduced 1994 by the US National Library of Medicine the digitized multimodal anatomical datasets of the Visible Man have challenged the worldwide scientific community. A significant response to this challenge from several interdisciplinary research teams has emerged as a new area of research. This area requires close interaction and collaboration among anatomists, radiologists, computer scientists, mathematicians, engineers and physicians. The digitized volumetric images of the human body have been applied not only for the computer-aided exploration of the human gross anatomy, but also as structural input for the therapy planning and simulation systems. The importance of such virtual patient model is becoming increasingly recognized in modern medicine. To effectively use these specific datasets a sophisticated framework consisting of image processing, computer graphics and mathematical modelling methods is required. In this work various aspects of the developed framework are presented and discussed. Some preliminary results of our biomedical simulations are presented.

Numerical treatment of registration problem in generation of patient-specific anatomical models

Chlebiej M., Król Z., Mikołajczak P.

Journal of Medical Informatics & Technologies

2003

Vol. 6

IT13--20

Registration is an important component of many medical data processing applications. Particularly significant is its role in the correlation of volumetric medical data aiming at generation of virtual patient-specific anatomical models. Such models enable optimization of various diagnostic and therapeutical procedures. The importance of the virtual patient models is becoming increasingly recognized in modern medicine. The advantages of using such biomedical virtual models are analogous to the advantages of real system behavior simulation in the engineering or material sciences. In this work some numerical issues associated with the registration problem and the visualization challenges arising in the context of virtual anatomical models have been presented and discussed.