In the paper some examples of reasoning with 2-uncertain rules are presented. First of all, they will illustrate the method for designing 2-uncertain rules from medical aggregate data. The obtained rules compose the knowledge base of a medical Rule-Based System (RBS) aiding medical diagnosis and treatment. For each obtained rule two determined factors of rules' reliability - global and internal ones - will rank it in the designed RBS. Furthermore, the presented examples will realize the influence of the reliability factors on the process of uncertain reasoning.
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