Investigations are presented for the preparation of a model hemostatic dressing that would exhibit an adequate hemostatic capacity in injuries and surgical wounds, an antibacterial activity to prevent primary and secondary infections, and offer safety in use. The Hemoguard dressing has been designed as a powder prepared from the complex chitosan/alginate Na/Ca in the form of micro- and nano-fibrids. Useful antibacterial and hemostatic properties of Hemoguard, which would qualify the material as first aid dressing and a temporary protection of injury wounds in field conditions, were assessed. Biocompatibility of the dressing was confirmed by biological in vitro examinations.
The paper presents chosen tests results of layers of cellulose nanofibres modified by bismuth subgallate towards applying to dressing materials. Cellulose nanofibers were prepared by the dry-wet spinning method. To prepare the spinning solution cellulose solvent N-Methylmorpholine-N-oxide (NMMO) were used. For model samples of layers of modified cellulose nanofibres findings of the haemolytic action and testing the sorption properties by in vitro method were presented. The test results show that assessed layers from modified cellulose nanofibres fulfill the requirements for the materials intended for the contact with blood as well as demonstrate the increased sorption what can cause faster activation of blood clotting inside the dressing materials in the result of stopping blood in the material. The research work was carrying out in the frame of project No. NN 507 379 135: Cellulose nanofibres for medical applications.
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.