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Sensitivity analysis of transient bioheat transfer during thermal injury formation of biological tissue

Jasiński M.

Journal of Applied Mathematics and Computational Mechanics

2014

Vol. 13, nr 2

33--42

The sensitivity analysis of the transient temperature field in the 2D tissue domain with respect to its thermophysical parameters is discussed. In particular, the influence of tissue specific heat, thermal conductivity, perfusion rate and metabolic heat source on the temperature distribution is considered. In order to determine the influence of variations of these parameters on temperature distribution, the direct approach of sensitivity analysis is applied. The algorithm of modeling of tissue injury withdrawal based on Arrhenius integral is also presented. At the stage of numerical realization the boundary element method is used. In the final part of paper the results obtained are shown.