Wyniki wyszukiwania - BazTech

Ograniczanie wyników

2 2005

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: tissue cultivation

Sortuj według:

Ogranicz wyniki do:

Inteligentne systemy bioreaktorów w tribologicznych procesach hodowli chrząstki stawowej

Wierzcholski K.

Problemy Eksploatacji

2005

nr 4

327--337

Badania procesu hodowli chrząstki w inteligentnych systemach bioreaktorów podczas nieustalonego laminarnego i turbulentnego przepływu nienewtonowskiej biologicznej cieczy odżywczej wokół chrząstki spoczywającej na rusztowaniu wymagają eksperymentalnego pomiaru chropowatości powierzchni chrząstki. Graniczna warstwa przyścienna cieczy biologicznej odżywczej na powierzchni chrząstki ma podczas hodowli wysokość od kilku do kilkudziesięciu mikronów. Dlatego nieregularności na powierzchni chrząstki o wysokości kilku mikrometrów mają istotne znaczenie w procesie sterowania hodowlą.

In this paper is presented the intelligent system of tissue cultivation. The study of cartilage cultivation in the bioreactor during hydrodynamic unsteady laminar flow of viscous biological non-Newtonian nutrient liquid flowing around the cartilage surface resting on the scaffold, demand the experimental measurements of surface roughness of cartilage. The boundary layer height of nutrient liquid on the cartilage surface during the cultivation has value from a few to anywhere from ten to twenty micrometers. Hence the irregularities of cartilage surfaces with deep about a few microns have important meaning in process of proper cultivation. Alterations of the subchondral bone that accompany the degeneration of articular cartilage include increased subchondral bone density and formation of cyst-like bone cavities containing myxoid or fibrous; or cartilaginous tissue; and the appearance of regenerating cartilage within and on the subchondral bone. At the end stage of the disease, the articular cartilage has been completely lost, leaving thickened, dense subchondral bone articulating with the similar opposing denuded bony surface. In this case the transplantation of the cultured cartilage is necessary. Surface roughness of tissue sample changes the friction forces and the direction of boundary velocity flow. Friction force is a function of dynamic viscosity of biological fluid and quantity of flow rate. Flow rate and direction of flow velocity change directly the tissue growth. By virtue of numerical calculations follows that velocity of tissue growth increases if flow rate increases and attain same critical value Q0. Further increases of the flow rate are not generated the increases of the superficial layer of cultured tissue. Obtained algorithm of calculated formulae enables to indicate the best values of flow rate of perfusion liquid to obtain optimal growth of tissue.

Thin layer of electrorheological liquids in bioreactors

Wierzcholski K. C.

International Journal of Applied Mechanics and Engineering

2005

Vol. 10, no spec

159-163

The electromagnetic fields have a great influence on the behaviour of all the nutrient liquids occurring in bioreactors and on the living tissue. Some benefits can be taken from the effects of the electromagnetic fields on the cultivating tissue in bioreactors, namely viscosity changes of nutrient liquids, hyperthermal conditions, friction force changes.