Tablet computers have become a common part of our life style. Since 2012, inspired by the success of touch devices in special education, we have established and led the IT therapy program for the mentally challenged. In this paper we also present one of our final study with 12 participants. Based on our findings from our studies we have finally proposed 14 design principles (an extension and redefinition of a previously proposed 10 simple design principles) which should be generally respected in design and development of every "usable/accessible" application for the mentally challenged. Some of these principles are applicable as design patterns or models in software development and some were already implemented in our framework which we used to develop new more usable applications.
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