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Biomateriały stosowane w inżynierii komórkowej i medycynie regeneracyjnej

Nowacka M.

Wiadomości Chemiczne

2012

[Z] 66, 9-10

909-933

Tissue engineering is a very rapidly developing domain of science. There is a huge interest in the biology of stem cells, especially in their proliferation, differentiation and spreading in the response to different factors. Biomaterials with properties similar to the natural environment of human body (accelerating wounds healing and not causing immunological response) as well as these that can control cells behavior are in constant need. This review presents the most popular polymeric biomaterials for tissue engineering and regenerative medicine [3–5, 8–20], explains interactions between cells and biomaterials [3, 13, 22–33], describes the most important surface properties that can have an influence on cells i.e. topography [36, 43–47, 53–72], roughness [1, 5, 31, 51, 66, 73–84], stiffness [54, 84–102], hydrophobicity, chemistry [4, 11, 16, 20, 27, 31, 32, 36–38, 42, 58, 103–112] and surface charge [18, 37, 113–116].