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Content available remote Computing the Length of Sum of Squares and Pythagoras Element in a Global Field
EN
This paper presents algorithms for computing the length of a sum of squares and a Pythagoras element in a global field K of characteristic different from 2. In the first part of the paper, we present algorithms for computing the length in a non-dyadic and dyadic (if K is a number field) completion of K. These two algorithms serve as subsidiary steps for computing lengths in global fields. In the second part of the paper we present a procedure for constructing an element whose length equals the Pythagoras number of a global field, termed a Pythagoras element.
EN
In this paper, we analyse the local stability of a gene-regulatory network and immunotherapy for cancer modelled as nonlinear time-delay systems. A numerically generated kernel, using the sum-of-squares decomposition of multivariate polynomials, is used in the construction of an appropriate Lyapunov–Krasovskii functional for stability analysis of the networks around an equilibrium point. This analysis translates to verifying equivalent LMI conditions. A delay-independent asymptotic stability of a second-order model of a gene regulatory network, taking into consideration multiple commensurate delays, is established. In the case of cancer immunotherapy, a predator–prey type model is adopted to describe the dynamics with cancer cells and immune cells contributing to the predator–prey population, respectively. A delay-dependent asymptotic stability of the cancer-free equilibrium point is proved. Apart from the system and control point of view, in the case of gene-regulatory networks such stability analysis of dynamics aids mimicking gene networks synthetically using integrated circuits like neurochips learnt from biological neural networks, and in the case of cancer immunotherapy it helps determine the long-term outcome of therapy and thus aids oncologists in deciding upon the right approach.
3
Content available remote On Sums of Four Coprime Squares
EN
It is proved that all sufficiently large integers satisfying the necessary congruence conditions mod 24 are sums of four squares prime in pairs.
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