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The contamination caused by pharmaceuticals is recognized as one of the most severe forms of environmental pollution. Many medicines and medical waste are dumped on the land, especially near hospitals, medical clinics, stores, and others, thus the aim of the study. The physical and mechanical of soil properties and tetracycline in leachate were studied. The sample extractor device (Shelby tube) was used to take undisturbed samples with a number of (6) tetracycline solutions added monthly to the soil samples, for a period of 6 months. The obtained results showed that silty clay is a type of this soil, the unconfined compression strength decreases with months to 6 months, while the effect on Atterberg’s limits (liquid and shrinkage limit) showed the soil became softer, lowering the value of the liquid limit. The tetracycline test in leachate water decreased with time, due to the soil adsorbed tetracycline. First-order is suitable for the kinetic model. Finally, the tetracycline drug effect on the physical and mechanical properties of soil was studied.
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