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A Method for Nucleotide Sequence Analysis

Kozarzewski B.

Computational Methods in Science and Technology

2012

Vol. 18, No. 1

5-10

Symbolic sequence decomposition into a set of consecutive, distinct subsequences (mers) is presented. Several statistical distributions of nucleotide subsequences are defined and analysed. Sequence entropy and similarity between sequences in terms of mer lengths distribution are defined. An alignment-free method of phylogenetic tree construction is proposed.