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1 Journal of Achievements in Materials and Manufacturing Engineering

1 2009

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Joule heating effects in capillary electrophoresis : designing electrophoretic microchips

Witkowski D., Łysko J., Karczemska A.

Journal of Achievements in Materials and Manufacturing Engineering

2009

Vol. 37, nr 2

592-597

Purpose: Computer simulations are widely used for designing, which contributes to a cheaper equipment developing process. In the last years computer simulations have begun to be also applied in different instances of microfluidics, especially in microchip electrophoresis (where an electrophoresis process takes place in the microcapillaries manufactured on the surface of the small plate) which is interesting for us. However, there are no many commercial programs enabling simulations of microfluidics. The programs existing in the market are recently developed as microscale brings new possibilities but also unpredictable effects and challenging problems. The aim of this paper is to develop a mature technique helpful in designing electrophoretic microchips [1-4]. Design/methodology/approach: Temperature distributions occurring during capillary electrophoresis because of Joule heating effects will be calculated with use of the CoventorWare™ software. Findings: Computer simulations with the model of capillary, with the same geometry as the real one, are presented. Numerical simulation results are compared with the real data from the capillary electrophoresis process. Practical implications: This is the first step to create a reliable tool for designing microfluidic devices. Originality/value: This comparison shows an ability of the CoventorWare™ software to design electrophoretic microchips.