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Elimination of ochratoxin A by lactic acid bacteria strains isolated from chickens and their probiotic characteristics

Kupryś-Caruk M., Stefańska I., Chabłowska B.

Biotechnology and Food Science

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2017

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Vol. 81, nr 2

113--124

EN

The aim of the study was to evaluate the ability of lactic acid bacteria strains, isolated from the gastrointestinal tract of chickens, to eliminate ochratoxin A (OTA) in vitro and to investigate whether the mechanism of OTA reduction is adsorption or hydrolysis. The probiotic characteristics of the strains, such as their growth performance and synthesis of lactic acid at 42°C, inhibition of Salmonella spp. and Escherichia spp. growth and susceptibility to antibiotics, was also evaluated. Ochratoxin A reductions in MRS broth depended on the tested strain and ranged from 1% to 29%. The level of OTA reduction was higher at 30°C than at 37 and 42°C and there were no significance differences between OTA reduction obtained with live and heat-treated bacteria cells. The evaluation of probiotic characteristics showed that Pediococcus acidilactici KKP 879 was the strain with more potential to develop a probiotic culture for chickens.

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Computational insights into the self-assembly of phenylalanine-based molecules

German H. W., Bhavaraju M., Uyaver S., Hansmann U. H. E.

TASK Quarterly : scientific bulletin of Academic Computer Centre in Gdansk

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2014

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Vol. 18, No 4

357--363

EN

In a recent paper “Self-Assembly of Phenylalanine-Based Molecules”, we h ave studied the formation and stability of phenylalanine and diphenylalani ne constructs. In the case of diphenylalanine we observe nanotubes, however, phenylalanin e molecules aggregate in layers of four, not six, molecules. In the preset paper, we extend this previous work and compare the energetics of all experimentally observed structures, s imulated structures, and designed structures, by way of single point Density Functional The ory ( DFT ) calculations. We take a detailed look at water content, pore size and dipole moments inside ou r phenylalaninecontaining tubes and analyze stabilizing factors in the nanostructures.

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Aminoalkylphosphines, theWater-Soluble Chiral Phosphines

Smoleński P., Pruchnik F. P.

Polish Journal of Chemistry

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2007

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Vol. 81, nr 10

1771-1771

EN

Chiral water-soluble heterocyclic phosphines 2,2',2''-[1,3,5-diazaphosphinane-1,3,5- triyltris(methyleneimino)]tripropanoic acid (1), 2,2',2''-[1,3,5-diazaphosphinane- 1,3,5-triyltris(methyleneimino)]tris(3-phenylpropanoic) acid (2) and 2,2',2''-[1,3,5-diazaphosphinane- 1,3,5-triyltris(methyleneimino)]tris(4-methylpentanoic) acid (3) were obtained in reactions of tris(hydroxymethyl)phosphine with chiral amino acids: alanine, phenylalanine and leucine. Course of reaction of amino acids depends on the acidity of solution, at pH 6mainly heterocyclic compounds were obtained, however in basic solutions products of Mannich-type condensation 2,2',2''-[phosphinetriyltris(methyleneimino)] tripropanoic acid (4), 2,2',2''-[phosphinetriyltris(methyleneimino)]tris(3-phenylpropanoic) acid (5) and 2,2',2''-[phosphinetriyltris(methyleneimino)]tris(4-methylpentanoic) acid (6) are formed. The prepared compounds were characterized using spectroscopic methods.

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A Fluorescence, 1H NMR spectroscopy and molecular dynamics study of the influence of rotamer population on fluorescence decay of tyrosine, phenylalanine and their derivatives

Ganzynkowicz R., Liwo A., Wiczk W.

TASK Quarterly : scientific bulletin of Academic Computer Centre in Gdansk

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2001

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Vol. 5, No 3

311-316

EN

Molecular dynamics simulations were carried out on tyrosine and phenylalanine and their derivatives with various terminal groups to determine the populations of side-chain rotamers. The obtained populations were compared with those calculated from fluorescence-decay lifetime distributions and NMR studies. It was found that theoretically calculated populations do not match the experimental ones, which suggests that the static rotamer model is inadequate to explain the dynamics of tyrosine and phenylalanine side chain in fluorescence and NMR experiments.