Wyniki wyszukiwania - BazTech

Ograniczanie wyników

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: parametr histomorfometryczny

Sortuj według:

Ogranicz wyniki do:

Mechanical and histomorphometrical evaluation of false and floating ribs of young adults with idiopathic scoliosis

Głowacki Jakub, Tomanik Magdalena, Pezowicz Celina, Krauss Hanna

Acta of Bioengineering and Biomechanics

2020

Vol. 22, no. 2

3--10

The aim of this paper was to assess the histomorphometrical and mechanical properties of ribs in patients with idiopathic scoliosis who underwent corrective surgery of scoliosis combined with thoracoplasty. Methods: The analyzed material encompasses 20 females between the ages of 12 and 18, whose pre-operative Cobb angle was 56.85 degrees, on average. The participants were divided into two age groups, up to the age of 15 and above 15 years old, taking into account the anatomical location of the assessed rib fragments with a division into floating and false ribs. The analysis of mechanical parameters was carried out by means of the quasi-static 3-point bending test, and the histomorphometric evaluation of the examined rib fragments was carried out using high-resolution computed tomography. Results: The existence of explicit relationships between selected radiological parameters describing scoliosis and mechanical and histomorphometric parameters of the ribs has not been confirmed. Statistically significant correlations between age and rib stiffness as well as between Young’s modulus and stiffness depending on the anatomical location of the examined rib fragment were confirmed. Conclusions: Mechanical and histomorphometric properties of bone tissue in patients with scoliosis are not explicitly associated with the radiological parameters characterizing scoliosis.

Investigation of microstructure of bone tissue in mandibles of newborn rats after maternal treatment with antiretroviral drugs

Filipek J., Binkowski M., Maciejewska K., Drzazga Z., Wróbel Z.

Biocybernetics and Biomedical Engineering

2015

Vol. 35, no. 1

54--63

High-resolution imaging has become a powerful tool for measurements in clinics, laboratory and animal studies, etc. In the present study, we aimed to investigate age related changes in bone development, and the effect of two antiretroviral agents (zidovudine and indinavir), which were administered during pregnancy, on the microstructure and bone mineral density (BMD) in newborn rats (7-, 14- and 28-day-old), with the use of X-ray microcomputed tomography (XMT). Fifty-four mandible bones were collected and divided into 3 groups: group 1 and 2: newborns after maternal treatment of zidovudine and indinavir respectively, group 3: control animals. The specimens were XMT scanned with the resolution of 7 μm and with a density phantom. Histomorphometric parameters and BMD were calculated to assess bone development depending on the administered drug. A statistical analysis was carried out to compare the differences among the control, zidovudine and indinavir groups. The analysis of the microstructure revealed disturbances in the development of the bone tissue in newborn rats. Indinavir seems to have a greater impact on bone microstructure than zidovudine.