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Gait changes in patients after reconstruction of facial bones with fibula and iliac crest free vascularized flaps

Syczewska M., Krajewski R., Szczerbik E., Kalinowska M.

Acta of Bioengineering and Biomechanics

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2018

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Vol. 20, no. 1

185--190

EN

Patients with malignant tumours of the oral cavity require its surgical removal and reconstruction of the bone and soft tissues. The grafts are obtained either from leg (fibula) or pelvis (iliac crest). The removal of grafts from the locomotor apparatus can impair the gait. The aim of this study was to find out how the localization of donor site influences the gait pattern. Methods: Results obtained for 30 patients were analyzed (16 fibula graft, 14 iliac crest graft). Patients underwent instrumented gait analyses three times (VICON system): before surgery, 2–4 month after the surgery, and 4–8 months after the surgery. Results: In both groups several gait parameters were changed. Two parameters changed in both groups: gait speed and cadence. In patients receiving iliac crest graft the changed gait variables were: pelvic rotation, hip range in sagittal plane (operated side), knee range in sagittal plane (operated side), foot dorsiflexion in swing on both sides. In patients receiving fibula flap the changed gait variables were: tilt, range motion of the tilt, minimum hip flexion (operated side), time to maximum knee flexion (non-operated side), GGI (non-operated side) and step length (nonoperated side). Conclusions: The primary gait deviations occurring after surgery, and the compensatory mechanisms which subsequently arise depend on the localization of graft donor site. The results indicate that the patients in whom fibula flap was used have less problems with gait pattern after the surgery than the patients receiving iliac crest graft.

2

Micronucleus assay in epithelial cells from the oral cavity and urinary tract in female smokers and non-smokers

Błaszczyk E., Mielzynska-Svach D.

Environmental Biotechnology

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2014

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Vol. 10, No. 2

60--65

EN

The aim of the work was to investigate the possible use of epithelial cells from the oral cavity and urinary tract in identifying smoking-related effects in women. Epithelial cells from the oral cavity and urinary tract were collected from 9 smoking and 9 non-smoking women and subjected to micronucleus assay. The DNA damage (cells with micronuclei and nuclear buds), cytokinetic defects (binucleated cells) and cell death (condensed chromatin, karyorrhexis, pyknosis and karyolysis) were observed after DNA specific staining. In pooled analysis of the frequency of binucleated cells and condensed chromatin cells in 18 studied women, statistically significant differences were noted only in epithelial cells from the oral cavity in comparison to those of the urinary tract. Non pooled results demonstrated no differences in damage frequency in cells collected from the oral cavity and isolated from the urine. The lack of differences in the observed frequencies of micronuclei in buccal and urothelial cells could be an effect of the small size of the sampled group, smoking pattern of the women and the number of cigarettes smoked per day.

3

Pasta do zębów. Cz. 2, Składniki aktywne

Kociołek-Balawejder E., Żebrowska M. K.

Przemysł Chemiczny

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2011

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T. 90, nr 6

1179-1185

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Pasta do zębów. Cz. 1, Składniki podstawowe

Kociołek-Balawejder E., Żebrowska M. K.

Przemysł Chemiczny

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2011

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T. 90, nr 6

1171-1178

5

An intraoral cone system for a Neptun 10PC linear accelerator

Shokrani P., Soltani P.

Nukleonika

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2011

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Vol. 56, No. 4

381-384

EN

Intraoral irradiation, the treatment choice for well defined oral-cavity tumors, is done using intraoral cone (IOC) systems. In this study, an IOC system was developed for a Neptun 10PC linac. Beam parameters necessary to plan an intraoral electron treatment were evaluated for two applicators, a flat and a beveled end. Measurements were performed using a Scanditronix (p-Si) diode field detector in a Scanditronix (RFAplus) 3-D (three-dimensional) water phantom. Percent depth dose distributions, beam profiles, and leakage dose distributions for the developed cone system are presented.

6

Disorder of the mineral metabolism of the oral cavity for patients with odontogenic absceses in maxillofacial area and ways for its correction with standard methods of rehabilitation

Kazakova Y. M., Pohodenko-Chudakova I. O.

Engineering of Biomaterials

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2009

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Vol. 12, no. 89-91

15--16

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Charakterystyka stateryny - białka śliny zaangażowanego w utrzymywanie homeostazy jamy ustnej

Jackiewicz-Barańska D., Kamysz E., Maćkiewicz Z.

Wiadomości Chemiczne

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2008

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[Z] 62, 7-8

595-608

EN

Saliva is a gel resembling liquid, that acts almost as an organic tissue [1]. Saliva influences oral health through its non-specific physico-chemical properties [2]. It is composed of secretions from parotid, submandibular and sublingual glands, and smaller contributions come from minor salivary glands (e.g. palatal and labial). Saliva contains a number of proteins and polypeptides [2]. One of them is statherin a multifunctional 43-amino acid residue phosphominiprotein, containing vicinal phosphoserines at 2 and 3 positions and seven residues of tyrosine (Fig. 1) [7]. The relevant structural feature of statherin is N-terminal helix segment connected to a long poly--L-proline type II segment, which is followed by a short extended structure [14]. The gene for statherin is believed to be a single-copy gene and has been mapped to human chromosome 4q11-13 [20]. The statherin variants are SV1, SV2 and SV3 which comprise approx. 30% of the statherin family (Fig. 6). The ratios of statherin : SV1 and SV2 : SV3 are in both cases approx. 3 : 1. Statherin and SV2 are products of two different transcripts found in each of the major salivary gland. The variants SV1 and SV3 are derived by post-translational processing of statherin and SV2 [22]. Statherin is a multifunctional molecule that shows a high affinity for calcium phosphate minerals such as hydroxyapatite. It takes part in the calcium and phosphate transport during secretion in the salivary glands, is responsible for the protection and recalcification of tooth enamel, promotes selective initial bacterial colonization of enamel, and functions as a boundary lubricant on the enamel surface [38, 39]. Satherin levels of concentration in saliva could be in relation with the precancerous and cancerous lesions of the oral cavity [38]. The understanding of a profile and role of statherin has become important in medicine as the peptide could play a protective effect in oral cavity. However, the role and the functions of this peptide are still not well-know [38].

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Zastosowanie leczenia fotodynamicznego z miejscową aplikacją kwasu 5-aminolewuliniowego w leukoplakii jamy ustnej

Kawczyk-Krupka A., Sieroń A., Suwała-Jurczyk B., Adamek M.

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna

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1999

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Vol. 5, nr 3-4

137-140

PL

Diagnostyka i terapia fotodynamiczna jest nową metodą rozpoznawania i leczenia stanów przednowotworowych i nowotworów skóry, jamy ustnej, przewodu pokarmowego, dróg oddechowych i dróg moczowych. Praca informuje o wynikach diagnostyki i leczenia fotodynamicznego 6 pacjentów z leukoplakią jamy ustnej. W ośrodku stosowano 10% kwas 5-aminolewulinowy (ALA) w maści, a następnie światło o długości fali 630 nm w dawce 100 J/cm2. Całkowite wyleczenie stwierdzono u 4 pacjentów. W pozostałych 2 przypadkach leczenie było nieskuteczne.

EN

Photodynamic diagnosis and therapy is known as a new method for treatment of precancerous and cancerous lesions of the skin, oral cavity, aerodigestive and urinary tracts. This study reports the use of PDD and PDT to diagnosis and treatment of 6 patients with leukoplakia of oral cavity. The10% 5-aminolevulinic acid (ALA) cream was applied to the oral leukoplakia lesions. Then light activated at 630 nm and 100 J/cm2 was used. Four patients show complete response to the treatment. In 2 patients treatment was unsuccessful.