In the paper optimization of operation process and minimization of operation cost for interconnected and interdependent critical infrastructure (CI) networks with cascading effects at variable operation conditions related to the climate-weather change are proposed. A multistate series network with assets dependent according to local load sharing (LLS) rule is analyzed and optimization of operation and safety of CI network with the LLS rule is introduced. For such CI network, the optimal transient probabilities that minimize the mean value of the total operation costs are found. Finally, cost analysis of CI network operation impacted by climate-weather change is presented in case the CI network is non-repairable and in case it is repairable after exceeding its critical safety state.
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