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EN
The morphological properties of retinal vessels are closely related to the diagnosis of ophthalmic diseases. However, many problems in retinal images, such as complicated directions of vessels and difficult recognition of capillaries, bring challenges to the accurate segmentation of retinal blood vessels. Thus, we propose a new retinal blood vessel segmentation method based on a dual-channel asymmetric convolutional neural network (CNN). First, we construct the thick and thin vessel extraction module based on the morphological differences in retinal vessels. A two-dimensional (2D) Gabor filter is used to perceive the scale characteristics of blood vessels after selecting the direction of blood vessels; thereby, adaptively extracting the thick vessel features characterizing the overall characteristics and the thin vessel features preserving the capillaries from fundus images. Then, considering that the single-channel network is unsuitable for the unified characterization of thick and thin vessels, we develop a dual-channel asymmetric CNN based on the U-Net model. The MainSegment-Net uses the step-by-step connection mode to achieve rapid positioning and segmentation of thick vessels; the FineSegment-Net combines dilated convolution and the skip connection to achieve the fine extraction of thin vessels. Finally, the output of the dual-channel asymmetric CNN is fused and coded to combine the segmentation results of thick and thin vessels. The performance of our method is evaluated and tested by DRIVE and CHASE_DB1. The results show that the accuracy (Acc), sensitivity (SE), and specificity (SP) of our method on the DRIVE database are 0.9630, 0.8745, and 0.9823, respectively. The evaluation indexes Acc, SE, and SP of the CHASE_DB1 database are 0.9694, 0.8916, and 0.9794, respectively. Additionally, our method combines the biological vision mechanism with deep learning to achieve rapid and automatic segmentation of retinal vessels, providing a new idea for diagnosing and analyzing subsequent medical images.
EN
Background and objective: Retinal image quality assessment is an essential task for the diagnosis of retinal diseases. Recently, there are emerging deep models to grade quality of retinal images. However, current models either directly transfer classification networks originally designed for natural images to quality classification of retinal images or introduce extra image quality priors via multiple CNN branches or independent CNNs. The purpose of this work is to address retinal image quality assessment by a simple deep model. Methods: We propose a dark and bright channel prior guided deep network for retinal image quality assessment named GuidedNet. It introduces dark and bright channel priors into deep network without extra parameters increasing and allows for training end-to-end. In detail, the dark and bright channel priors are embedded into the start layer of a deep network to improve the discriminate ability of deep features. Moreover, we re-annotate a new retinal image quality dataset called RIQA-RFMiD for further validation. Results: The proposed method is evaluated on a public retinal image quality dataset Eye-Quality and our re-annotated dataset RIQA-RFMiD. We obtain the average F-score of 88.03% on Eye-Quality and 66.13% on RIQA-RFMiD, respectively. Conclusions: We investigate the utility of the dark and bright channel priors for retinal image quality assessment. And we propose a GuidedNet by embedding the dark and bright channel priors into CNNs without much model burden. Moreover, to valid the GuidedNet, we re-create a new dataset RIQA-RFMiD. With the GuidedNet, we achieves state-of-the-art performances on a public dataset Eye-Quality and our re-annotated dataset RIQA-RFMiD.
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