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EN
Positronium imaging is a new technique complementary to positron emission tomography (PET) based on the histogramming of time delay between the emission of a de-excitation photon, and a consequent electron-positron annihilation, to estimate the mean lifetime of orthopositronium (o-Ps), which depends on the local size of the voids, concentration of oxygen and bioactive molecules. We improve the resolution and reduce noise in positronium imaging by building time-delay spectra from the PET activity reconstructed by a 3-photon time-of-flight maximum likelihood expectation maximisation. The method was tested on the data measured for four human-tissue samples injected by 22Na and put in the Jagiellonian PET “Big barrel” scanner. Due to an ill-posed problem of fitting time-delay histograms, a multistage optimisation procedure was explored along with inferential analysis of the solution space. Run in parallel for multiple sets of initial guesses, we compared the second-order LevenbergMarquardt algorithm (LMA) and the direct search Nelder-Mead simplex (NMS) method. The LMA proved to be faster and more precise, but the NMS was more stable with a higher convergence rate. The estimated mean o-Ps lifetimes in the 1.9 ns - 2.6 ns range were consistent with the reference results, while other fitting parameters allowed differentiation between the two patients who provided the tissue samples.
EN
A study branch that mocks-up a population of network of swarms or agents with the ability to self-organise is Swarm intelligence. In spite of the huge amount of work that has been done in this area in both theoretically and empirically and the greater success that has been attained in several aspects, it is still ongoing and at its infant stage. An immune system, a cloud of bats, or a flock of birds are distinctive examples of a swarm system. In this study, two types of meta-heuristics algorithms based on population and swarm intelligence - Multi Swarm Optimization (MSO) and Bat algorithms (BA) – are set up to find optimal solutions of continuous non-linear optimisation models. In order to analyze and compare perfect solutions at the expense of performance of both algorithms, a chain of computational experiments on six generally used test functions for assessing the accuracy and the performance of algorithms, in swarm intelligence fields are used. Computational experiments show that MSO algorithm seems much superior to BA.
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