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Content available remote Nanodiamonds
EN
Purpose: Diamond nanoparticles have been found in DLC films, in detonation products of explosives and in some type of meteorites. In this paper the results of physico-chemical examinations - also in vitro and in vivo - of Nanocrystalline Diamond Powder Particles (DPP) and Detonation Nanodiamond (DND) are reported. Design/methodology/approach: Material characterizations of DPP have been evaluated by using: Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), Auger electron spectroscopy (AES), microX-Ray Spectroscopy. Biological investigation based on: (a) in vivo and (b) in vitro examinations as well (c) clinical investigations - contact allergy. Findings: It has been proven that Diamond Powder Particles (DPP) may act as antioxidant and/or anti-inflammatory factors when applied in living systems. It seems probable that reactions between the diamond surface and some biologically important molecules play a significant role in this process. Research limitations/implications: The mechanism of antioxidant and/or anti-inflammatory behavior of DPP is not yet fully understood. Practical implications: Nanocrystalline diamonds can be dispersed in a biologically acceptable carrier to form various compositions. DPP can be included in a cream having bioactive properties. Originality/value: Bioactivity of Diamond Powder Particles.
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