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The effect of intraocular pressure on chick eye geometry and its application to myopia

Genest R., Chandrashekar N., Irving E.

Acta of Bioengineering and Biomechanics

2012

Vol. 14, no. 2

3-8

Myopia is characterized by an increase in axial length of the eye, but the reasons for the axial elongation are still unknown. Higher intraocular pressure (IOP) has been associated with myopia and could be involved in eye enlargement. The purpose of this study was to investigate the effect of intraocular pressure on the geometry of the chick eye and to investigate whether an increase in IOP could cause the elongation of the eye. The IOP of ten 7-day old chick eyes was raised by injecting fluid into the eyes and the resulting deformation of the eyes was measured using digital cameras. In-vitro pressure-volume curves were obtained. The axial and equatorial strains (deformation normalized to the original dimension) were calculated. Our results showed that IOP increased exponentially with increasing injected volume. About 25 D myopia could be induced by the axial elongation created with an increase in IOP by 100 mmHg. As pressure increased from 0 to 140 mmHg, the chick eye elongated in the axial direction and initially contracted in the equatorial direction. The natural tendency of chick eyes is to elongate as IOP increases and this suggests that from a mechanical perspective IOP could play a role in myopia onset and progression. The results also suggest that oblate eyes might have higher risk of developing myopia.

Przegląd zastosowań laserów ekscymerowych w chirurgii oka

Garncarz B.

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna

1998

Vol. 4, nr 4

157-162

Praca zawiera przegląd zastosowań laserów ekscymerowych do modelowania przedniego odcinka oka. LASIK (laser in situ keratomileusis) jest nąjnowocześniejszą z metod korekcji wad wzroku będącą kombinacją techniki operacyjnej połączoną z leczeniem za pomocą lasera ekscymerowego Podczas wykonywania tego zabiegu warstwa Bowmanna pozostaje nienaruszona. Metodę tę można stosować nawet do -20 D. Praca ukazuje szerokie możliwości wykorzystania laserów w okulistyce.

This review describes optical methods related to excimer laser surgery of the anterior eye segment. Laser in situ keratomileusis (LASIK) is a technique combining the advantages of lamellar corneal surgery, not destructive to Bowman's layer, with the precision of excimer laser surgery. It can be used to correct myopia in a wide range of diopters (to -20 D). This review covers some aspects of laser application in ophthalmology, as photorefractive surgery (PRK) and LASIK.