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2 Polish Journal of Chemistry

2 Dzierzbicka K.

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Synthesis of New Conjugates of MDP and nor-MDP with Retro-Tuftsin Derivatives as Potential Immunomodulators

Dzierzbicka K.

Polish Journal of Chemistry

2008

Vol. 82, nr 7

1431-1431

Synthesis of new conjugates of muramyl dipeptide (MDP) and nor-muramyl dipeptide (nor-MDP) with retro-tuftsin derivatives is presented. The corresponding protected retro-tuftsin derivatives were also synthesized. The synthesis of a greater number of conjugates will enable structure-activity relation ship studies.

Synthesis of Conjugates of Muramyl Dipeptide and nor-Muramyl Dipeptide with Retro-Tuftsin (Arg-Pro-Lys-ThrOMe) as Potential Immunostimulants

Dzierzbicka K.

Polish Journal of Chemistry

2004

Vol. 78 / nr 3

409-416

The synthesis of retro-tuftsin analogue of sequence Arg-Pro-Lys-ThrOMe (Scheme 1) and it's conjugates containing MDP (muramyl dipeptide) or nor-MDP (nor-muramyl dipeptide) (Scheme 2) are described.