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Continuous mathematical models of airlift bioreactors: Families, affinity, diversity and modelling for single-substrate kinetics

Grzywacz R.

Chemical and Process Engineering

2012

Vol. 33, nr 2

291-309

This paper presents a method of describing an airlift bioreactor, in which biodegradation of a carbonaceous substrate described by single-substrate kinetics takes place. Eight mathematical models based on the assumption of liquid plug flow and axial dispersion flow through the riser and the downcomer in the reactor were proposed. Additionally, the impact of degassing zone with assumed complete mixing on the obtained results was analyzed. Calculations were performed for two representative hydrodynamic regimes of reactor operation, i.e. with the presence of gas bubbles only within the riser and for complete gas circulation. The conclusions related to the apparatus design and process performance under sufficient aeration of the reaction mixture were drawn on the basis of the obtained results.

Catalytic semipermeable membrane - challenge and possibilities

Noworyta A.

Biocybernetics and Biomedical Engineering

2008

Vol. 28, no. 2

35-47

Equations describing a multi-phase bioreactor with a catalytic membrane located on the boundary of phases, of which one is a substrate reservoir, are formulated. A model analysis of the process was carried out and the effect of main operating parameters of such a reactor, i.e. the catalytic layer thickness and the coefficients of diffusion mass transport in both phases, was determined. Two periods with different methods of supplying the catalytic layer can be distinguished in the process. There is also a characteristic thickness of the catalyst layer and when it is exceeded the process duration is no longer shortened although not always full substrate conversion from the supply stream has a place. It is recommended to apply thin layers, because then the catalyst activity is fully used. The analyse of the influence of mass transfer showed that substrate mass transfer in acceptor phase to the catalyst layer has a slight effect on the process rate when the intensification of its transfer in donor phase could have a significance influence on process rate.