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A Foundational Framework for Step-by-step Model Construction

Barash M., Petre I.

Fundamenta Informaticae

2017

Vol. 154, nr 1/4

15--24

Constructing large biomodels de-novo is a computationally expensive process, requiring large sets of high-quality data. An alternative approach is to construct them from smaller existing models through various operations such as union, intersection, difference, and refinement. We introduce in this paper a foundational framework for biomodel construction capturing these operations, and we discuss some of their properties.