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1
Content available Design and fabrication of 125I seeds for brachytherapy using capillary-based microfluidic technique
Wang Yuan, Zhang Miao, Song Tong, Chang Zhenqi
Nukleonika
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2021
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Vol. 66, No. 2
55--60
EN
A new kind of 125I seeds with a core-shell structure were synthesized by an easy assembling–disassembling coaxial capillaries microfluidic device. The dose distribution of a 125I brachytherapy source fabricated by arranging six 125I seeds collinearly within a cylindrical titanium capsule was simulated by modelling the source in a water phantom using Monte Carlo N-Particle Transport code. The infl uence of the motion and the core size of the 125I seeds on the dose distribution was also studied in this work.
2
Content available Numerical study of droplet formation in a Y-junction microchannel
Diouf M. M. L., Romero O. J.
Journal of Theoretical and Applied Mechanics
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2017
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Vol. 55 nr 1
317--330
EN
This study investigates the formation process of droplets in a Y-junction microchannel using two immiscible fluids: water as the continuous fluid and oil as the dispersed phase. We have examined the influence of the capillary number, flow rate ratio and viscosity ratio between the two fluids; parameters which determine the length and generation frequency of the droplets. Numerical simulations have been performed using the software Ansys Fluent with the interface capture method Volume of Fluid (VOF) for solving the governing equations. Three different algorithms have been tested for the pressure-velocity coupling: SIMPLE, SIMPLEC and PISO. The results are quite similar for SIMPLE and SIMPLEC, however it turned out that PISO is a better algorithm to solve the two-phase flow. Additionally, another Y-junction is coupled in the initial geometry to observe a symmetric breakup of the droplets and their formation is explained using the pressure field and the velocity field.
3
Content available Lab-on-a-chip microdevice with contactless conductivity detector
Blaszczyk K., Chudy M., Brzozka Z., Dybko A.
Metrology and Measurement Systems
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2013
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Vol. 20, nr 2
299--306
EN
This paper describes a new contactless conductivity detector, whose electrodes are constructed of microchannels filled with solution of KCl - called pseudoelectrodes. The lab-on-a-chip microdevice was fabricated in poly(dimethylsiloxane) PDMS, using a moulding technique. The mould was made from a dry negative photoresist with a thickness of 50 µm. During the tests, the dimension and arrangement of pseudoelectrodes' microchannels were evaluated. The analyte was pumped into the microchannel using a syringe pump with a flow rate of 50 µL/min. Reproducible changes of the signal were obtained.
4
LTCC microfluidic chip with fluorescence based detection
Czok M., Malecha K., Golonka L.
Elektronika : konstrukcje, technologie, zastosowania
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2012
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Vol. 53, nr 1
37-39
EN
This paper presents development and manufacturing processes of the fluorescence based microfluidic chip using Low Temperature Co-fired Ceramics technology (LTCC). The LTCC material was chosen because of its outstanding physical and chemical properties. Moreover, there is a possibility to integrate electronic and optoelectronic components into single LTCC microfluidic chip. The manufactured microfiuidic chip consists of inexpensive and commonly available electronic components and PMMA (poly(methyl methacrylate)) optic fibres. Its performance is investigated with a fluorescent dye. Five different fluorescein solutions are excited with 465 nm light source, and then the intensity of the emitted fluorescent light is measured with two photodelectors. The performed experiments have shown that it is possible to detect fluorescent signal inside the LTCC microfluidic chip using commonly available optoelectronic components.
PL
W artykule opisano proces wytwarzania mikroprzepływowego czujnika fluorescencyjnego, w technologii niskotemperaturowej ceramiki współwypalanej LTCC (Low Temperature Co-fired Ceramics Technology]. Wykonany czujnik składa się z tatwo dostępnych i niedrogich elementów elektronicznych, a także z polimerowych światłowodów PMMA (polimetakrylan metylu]. Pracę mikroprzepływowego czujnika ceramicznego zbadano za pomocą barwnika fluorescencyjnego. W tym celu przygotowano pięć różnych stężeń fluoresceiny w etanolu. Roztwory testowe pobudzano źródłem promieniowania, o długości fali równej 465 nm, a następnie mierzono (dwoma fotodetektorami) natężenie wyemitowanej wiązki światła. Przeprowadzone badania wykazały, że możliwa jest detekcja sygnału fluorescencyjnego, wewnątrz mikroprzepływowego czujnika ceramicznego, za pomocą powszechnie dostępnych elemenlów optoelektronicznych.
5
Content available Integration of optoelectronic components with LTCC (low temperature co-fired ceramic) microfluidic structure
Malecha K.
Metrology and Measurement Systems
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2011
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Vol. 18, nr 4
713-721
EN
Investigations on integration of optoelectronic components with LTCC (low temperature co-fired ceramics) microfluidic module are presented. Design, fabrication and characterization of the ceramic structure for optical absorbance is described as well. The geometry of the microfluidic channels has been designed according to results of the CFD (computational fluid dynamics) analysis. A fabricated LTCC-based microfluidic module consists of an U-shaped microchannel, two optical fibers and integrated light source (light emitting diode) and photodetector (light-to-voltage converter). Properties of the fabricated microfluidic system have been investigated experimentally. Several concentrations of potassium permanganate (KMnO4) in water were used for absorbance/transmittance measurements. The test has shown a linear detection range for various concentrations of heavy metal ions in distilled water. The fabricated microfluidic structure is found to be a very useful system in chemical analysis.
6
Content available remote Application of porous glasses in microfluidic devices
Evstrapov A.A., Esikova N.A., Rudnitskaja G.E., Antropova T.T.
Optica Applicata
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2008
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Vol. 38, nr 1
31-38
EN
Nowadays a perspective appears of applying porous glasses in microanalytical devices. The opportunity of application of porous glasses as optical sensors has been shown in the present paper. Preliminary results of studying the electroosmotic flows through porous glasses are discussed.
7
Content available remote Zagadnienia montażu mikrozaworów pneumatycznych
Dindorf R.
Napędy i Sterowanie
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2007
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R. 9, nr 7/8
104-108
PL
Rozwój mikropneumatyki odpowiada trendowi rozwoju współczesnej techniki - robotyki, automatyzacji produkcji, motoryzacji, techniki medycznej i rehabilitacyjnej, lotnictwa i astronautyki. Obserwuje się wzrastające zapotrzebowanie na zminiaturyzowane zawory i mikrozawory pneumatyczne, które charakteryzują się małymi wymiarami, zminimalizowanym zużyciem energii, krótkim czasem przesterowania oraz małą przepustowością. W referacie scharakteryzowano wybrane zagadnienia montażu mikrozaworu na przykładzie bistabilnego zaworu foliowego. W mikrosystemach technicznych MST (ang. Microsystem Technology) występują mikrosystemy płynowe (ang. Microfluidic), które dotyczą zarówno mikrohydrauliki, jak i mikropneumatyki [3]. W systemach tych występują zawory w postaci zminiaturyzowanej o wymiarach nominalnych kilku milimetrów oraz mikrozawory o wymiarach nominalnych od kilku do kilkuset mikrometrów. W mikrosystemach elektromechanicznych MEMS (ang. Micro Eletro-Mechnical System) wyróżnia się technikę zminiaturyzowaną, mikrotechnikę i nanotechnikę.
8
Content available remote X-ray microdiffraction on flow-controlled biomolecular assemblies
Evans H.M., Dootz R., Köster S., Pfohl T.
Bulletin of the Polish Academy of Sciences. Technical Sciences
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2007
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Vol. 55, nr 2
217-227
EN
The study of liquid crystalline assemblies, with an emphasis on biological phenomena, is now accessible using newly developed microdevices integrated with X-ray analysis capability. Many biological systems can be described in terms of gradients, mixing, and confinement, all of which can be mimicked with the use of appropriate microfluidic designs. The use of hydro-dynamic focusing creates well-defined mixing conditions that vary depending on parameters such as device geometry, and can be quantified with finite element modelling. We describe experiments in which geometry and strain rate induce finite changes in liquid crystalline orientation. We also demonstrate the online supramolecular assembly of lipoplexes. The measurement of lipoplex orientation as a function of flow velocity allows us to record a relaxation process of the lipoplexes, as evidenced by a remarkable 4-fold azimuthal symmetry. All of these processes ale accessible due to the intentional integration of design elements in the microdevices.
9
Content available remote Technology and applications of Low Temperature Cofired Ceramic (LTCC) based sensors and microsystems
Golonka L.J.
Bulletin of the Polish Academy of Sciences. Technical Sciences
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2006
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Vol. 54, nr 2
221-231
EN
The paper presents general information on LTCC materials, manufacturing processes and properties of fired modules. A Multichip Module package has been the main application of Low Temperature Cofired Ceramic (LTCC) technology. Recently, this technology is also used for production of sensors, actuators and microsystems. The research and development on the LTCC sensors and microsystems carried out in the Laboratory of Thick Film Microsystems at Wroc1aw University of Technology are presented. LTCC microfluidic system is described in detail. Moreover, a short information is given on other LTCC applications.
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