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1

Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy

Kalicka R., Browarczyk M., Lipiński S.

Biocybernetics and Biomedical Engineering

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2015

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Vol. 35, no. 1

68--73

EN

This paper presents the usefulness of perfusion computed tomography (pCT) in the diagnosis of diabetic pulmonary microangiopathy. Our previous works have shown that perfusion parameters are useful in the diagnosis of diabetic pulmonary microangiopathy. We are looking for such measurements and perfusion parameters that provide the most accurate diagnosis. Two types of comparison were made based on the results of clinical trials: non-diabetic vs. diabetic and diabetes without microangiopathy vs. diabetes with microangiopathy. Our studies have shown that PS (permeability surface) is only perfusion parameter statistically significant. In certain regions of interest logistic regression as a classifier produces very good results in diagnosing lung microangiopathy: sensitivity Sens = 89% and excellent specificity Spec = 100%. The results were obtained on the base of measurements taken from 23 subjects. These results were compared with results reported in the literature and based on diffusion capacity and spirometry measurements and modeling. None of the previous results was as good as those obtained using the PS and logistic regression for binary classification.

2

Heavy metal distribution in organisms of hares, roe deer and foxes

Wieczorek J., Gambuś F.

Chemia i Inżynieria Ekologiczna

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2005

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Vol. 12, nr 1-2

127-133

EN

The aim of research were studies on heavy metal distribution in bodies of hares, roe deer and foxes. Contents of cadmium, chromium, lead and zinc were determined in the samples of kidneys, livers, lungs, musc1es and bones of the tested animals originating from the vicinity of Kraków. A majority of the analysed material samples contained on average largest quantities of zinc, then lead and chromium and the least of cadmium. Only in the kidneys and livers of hares and roe deer cadmium concentrations were much higher than lead and chromium content in these organs. It was also noticed that more cadmium, chromium and zinc, in comparison with this metal in fox organs, accumulated in the internal organs and tissues of hares and roe deer than in the analogous fox organs. The dependency concerns particularly cadmium content in the kidneys and livers of tested herbivorous where between 20 and 30 and 3-5 times more of this metal was found, respectively in comparison with its concentrations in the same organs of rex. Lead most easily accumulated in tissues and internal organs of rex, particularly in its bones (mean 10.8 mg . kg-1 d.m.) and in the lungs (7.76 mg . kg-1 d.m.).

PL

Celem niniejszych badań było prześledzenie rozmieszczenia metali ciężkich w ciele zajęcy, saren i lisów. W próbkach nerek, wątroby, płuc, mięśni i kości osobników pochodzących z okolic Krakowa określono zawartość kadmu, chromu, ołowiu i cynku. W większości próbek analizowanych materiałów średnio najwięcej oznaczono cynku, następnie ołowiu, chromu i kadmu. Jedynie w nerkach i wątrobie zajęcy i saren koncentracja kadmu była znacznie większa od zawartości ołowiu i chromu w tych organach. Stwierdzono również, że w narządach i tkankach zajęcy i saren nagromadzało się więcej kadmu, chromu i cynku w porównaniu do analogicznych organów lisa. Zależność ta szczególnie dotyczy zawartości kadmu w nerkach i wątrobie badanych roślinożerców, gdzie oznaczono odpowiednio 20-30 i 3-5 razy więcej tego metalu w porównaniu do jego koncentracją w tych samych narządach lisa. W przypadku ołowiu najwięcej odkładało się go w organach lisa, szczególnie w jego kościach (10,8 mg) i płucach (7,76 mg . kg-I s.m.).

3

Stimulation of nerves innervating the pancreas of a dog

Rozman J., Trlep M., Zorko B., Bunc M.

Journal of Technical Physics

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2002

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Vol. 43, no 4

467-473

EN

The purpose of the study was to evaluate the influence of electrical stimulation of nerves innervating the pancreas on the function of the cardiovascular system, lungs and urinary tract, measured as an ECG, blood pressure and pressure in the bladder of a dog. Spiral cuffs with 33 electrodes (1.0 x 2.0 mm) within a silicone sheet were manufactured and implanted in a Beagle dog in the vagus nerve, in the splanchnic nerve and in the pancreatic nerve. Each nerve was stimulated individually with biphasic, rectangular and current pulses (10 mA, 200 [my]s, 20 Hz). When stimuli were 10 mA or higher, measurable changes were observed during stimulation of both the vagus and the splanchnic nerves. In the splanchnic nerve, they were expressed as an increase in pressure in the bladder and as a tremor of the whole stomach. In the vagus nerve, they were expressed as a drastic decrease of arterial blood pressure and as abnormalities in the heart rate. In a further increase of stimuli to about 18 mA, the heart rate was slowed until it ceased as fatal brachicardia, asystolia and consequently hypotensia was occured.