Wyniki wyszukiwania - BazTech

Ograniczanie wyników

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: kinaza

Sortuj według:

Ogranicz wyniki do:

Evaluation of the effectiveness of training on a machine with a variable-cam

Urbanik C., Staniszewski M., Mastalerz A., Karczewska M., Lutosławska G., Iwańska D., Madej A., Ostrowska E., Gwarek L., Tkaczyk J.

Acta of Bioengineering and Biomechanics

2013

Vol. 15, no. 4

93--102

The aim of the study was to assess the effectiveness of the training of elbow flexors through the use of 2 machines, one of which was equipped with a disc plate of constant radius, the other one with a variable-cam having a radius adjustable to muscle strength. The experiment included 45 men divided into 3 equal groups: training group A (variable-cam), training group B (circle), and control group C. The training lasted for 8 weeks, 3 times a week. In order to control the effects, the values of peak torque and power of the flexor muscles of the elbow were isokinetically measured for the angular velocities of 30°/s and 60°/s. Also taken were anthropometric measurements of the arm and the creatine kinase (CK) activity in the blood plasma. As a result of the training, significant increases of biomechanical values were noted only in group A: power increased over 20%, the peak torque over 14%. After the training, significant increases of arm circumference in the relaxed position were noted in group A (17 mm), as well as in group B (11 mm). Also, some changes in CK activity were observed between Monday and Friday in a training week. On the basis of the experimental measurements, it may be ascertained that training elbow flexor muscles on a machine with a variable-cam is more efficient for increases in strength and power, as well as for some anthropometric parameters, than training on a machine with a disc plate.

Signal transfer in the cellular response to ionizing radiation

Szumiel I., Sochanowicz B.

Nukleonika

1998

Vol. 43, nr 2

133-146

Numerous factors have recently been identified that are involved in the control of cell cycle checkpoints. It was found that the DNA damage-induced G1 and G2 delays are associated with a regulatory system consisting of cyclin-dependent protein kinases (CDKs) associated with cell cycle phase specific cyclins. This article reviews the recently discovered associations between cell cycle regulation and cell death or recovery in the in vitro cellular systems exposed to ionizing radiation. The concept of alarm signal is explained. A brief comment on the role of apoptosis in the postirradiation cell fate is included.

W ostatnich latach zidentyfikowano liczne czynniki mające udział w regulacji przechodzenia komórek przez punkty kontrolne cyklu komórkowego. Okazało się, że indukowane przez uszkodzenie DNA bloki w fazach G1 i G2 regulowane są przez cyklinozależne kinazy białkowe, CDK. Praca jest przeglądem nowo odkry1ych powiązań między śmiercią lub odnową popromienną komórek a układem regulującym cykl komórkowy w układach in vitro. PQnadto wyjaśnione jest pojęcie sygnału alarmowego oraz skomentowana rola apoptozy w losie napromienionej komórki.