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EN
Isocyanides are compounds with a triple bond between a nitrogen atom and a carbon atom. Thanks to this structure, there is an electron lone pair on the carbon atom, which allows these compounds to participate in many reactions in organic chemistry. Due to their properties and the number of reactions in which they can participate, this group has been applied in medicine. Both natural and synthetic isocyanides have antifungal, antibacterial, antimalarial, antiviral and anticancer properties. The reactions involving them allow for a much simpler and faster synthesis of many pharmaceuticals. In addition, these compounds have application properties, making it possible to obtain polymers. Despite the polymerization of these compounds raising many objections, many polymeric materials based on isocyanides have found applications both in science and in everyday life.
EN
Isocyanides are the most unusual and unique group in organic chemistry. They possess an unusual valence structure and reactivity. Isocyanides are the only class of stable organic compounds with a formal divalent carbon, which allows them to be the subject of virtually all reactions in organic chemistry. It can be either an electrophile, a nucleophile, a caraben and a radical acceptor. We distinguish between naturally occurring and synthetically produced isocyanides. Both groups of isocyanides have become recently the subject of scientific interest.
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