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Single-domain nanoparticle magnetic power losses calibrated with calorimetric measurements

Miaskowski A., Sawicki B., Subramanian M.

Bulletin of the Polish Academy of Sciences. Technical Sciences

2018

Vol. 66, nr 4

509--516

The purpose of this study was to establish a numerical model for calorimetric measurements of magnetic fluids under an alternating magnetic field (AMF). The modified linear response theory (LRT) and Stoner-Wohlfarth theory were applied to investigate heat dissipation from the ferrofluid. The hysteresis area was calculated once the magnetic field value, applied frequency and number weighted distribution of the nanoparticles were known. Magnetic field distribution was calculated for the setup used for performing calorimetric experiments, and field dependent relaxation times were employed to calculate the specific loss power (SLP) in the sample. Subsequently, the results of numerical investigation were compared with the measurements obtained from calorimetric experiments. The Zeeman energy condition was used to delimit the area where LRT is valid. The numerical model calibrated with the calorimetric measurements allowed for the diffusion coefficient and the parameters involved in power dissipation in a ferrofluid to be determined. These parameters were then used to compute total heat dissipation and temperature distribution within the sample. The numerical model matching the calorimetric measurements of heat dissipation from ferrofluids enhanced the reliability of simulations.

Numerical model of magnetic fluid hyperthermia

Sawicki B., Miaskowski A.

Przegląd Elektrotechniczny

2013

R. 89, nr 7

86--88

The article presents the computer model of magnetic fluid hyperthermia (MFH), which is new, promising cancer treatment. Special attention was focused on the complete mapping of physical and biological phenomenon, such as a realistic model of magnetic field excitement, blood perfusion, metabolic heat and convective heat exchange with the environment. The described model was implemented using the finite element method.

Artykuł prezentuje metodyke numerycznego modelowania hipertermii płynu magnetycznego (ang. MFH), ktora jest nową, obiecującą techniką leczenia nowotworów. Specjalna uwaga została zwrocona na pełne odwzorowanie zjawisk fizycznych i biologicznych, takich jak: realistyczny model wymuszenia magnetycznego, zjawisko perfuzji krwi, metaboliczne źrodła ciepła oraz zjawisko konwekcyjnej wymiany ciepła z otoczeniem. Opisany model został zaimplenemtowany przy wykorzystaniu metody elementów skończonych.