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Feature Selection and Classification Pairwise Combinations for High-dimensional Tumour Biomedical Datasets

Wosiak A., Dziomdziora A.

Schedae Informaticae

2015

Vol. 24

53--62

This paper concerns classification of high-dimensional yet small sample size biomedical data and feature selection aimed at reducing dimensionality of the microarray data. The research presents a comparison of pairwise combinations of six classification strategies, including decision trees, logistic model trees, Bayes network, Naıve Bayes, k-nearest neighbours and sequential minimal optimization algorithm for training support vector machines, as well as seven attribute selection methods: Correlation-based Feature Selection, chi-squared, information gain, gain ratio, symmetrical uncertainty, ReliefF and SVM-RFE (Support Vector Machine-Recursive Feature Elimination). In this paper, SVMRFE feature selection technique combined with SMO classifier has demonstrated its potential ability to accurately and efficiently classify both binary and multiclass high-dimensional sets of tumour specimens.