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1 2005

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On graph theoretical models for peptide sequence assembly

Błażewicz J., Borowski M., Formanowicz P., Głowacki T.

Foundations of Computing and Decision Sciences

2005

Vol. 30, No. 3

183-191

The amino acid sequences of proteins determine their structure and functionality, hence methods for reading such sequences are crucial for many areas of biological sciences. Obviously, the genetic information encoding proteins is written in DNA however, knowing gene sequences is not always sufficient for determining the corresponding amino acid sequences. Since direct methods for reading amino acid seqeunces allow for determination of only very short fragments, some methods for assembly of these fragments are required. In this paper, we show and analyze some graph theoretic models of the peptide sequence assembly process.