Wyniki wyszukiwania - BazTech

1

Fabrication and Characterization of Fibrous Polycaprolactone Blended with Natural Green Tea Extracts Using Dual Solvent Systems

Mohd Rashid Ainatul Aqilah Binti, Jaganathan Saravana Kumar, Mohd Khudzari Ahmad Zahran, Ismail Ahmad Fauzi

Autex Research Journal

|

2022

|

Vol. 22, no. 4

404--410

EN

Nanofibrous dressings serve as an impeccable candidate in the management of wounds. Nanofibrous composites composed of polycaprolactone (PCL) and green tea using dual solvent systems at different ratios were fabricated through electrospinning. Pure PCL electrospun fibers along with composites were characterized by using scanning electron microscopy (SEM), wettability, water uptake analysis, and Fourier transform infrared spectroscopy (FTIR). SEM indicated that fibrous morphology and the diameter of PCL/green tea were smaller for chloroform/ dimethylformamide (DMF) (601 nm) and acetone/DMF (896 nm) than the pure PCL (673 nm and 1,104 nm for chloroform/DMF and acetone/DMF, respectively). Wettability of the fabricated composites was increased, and pure PCL fibers were slightly more hydrophobic (100°) than PCL/green tea (94°). Water uptake of the composites was enhanced compared with PCL significantly in acetone/DMF. The PCL/green tea nanofibrous wound dressing with enhanced physicochemical properties serves as an indispensable candidate for wound healing applications.

2

Dekstran i jego pochodne w inżynierii tkanek miękkich - opatrunki do leczenia ran trudno gojących się

Szafulera K.

Eliksir

|

2016

|

nr 1

32--37

3

The influence of ambient temperature on foot temperature in patients with diabetic foot ulceration

Foltyński P., Mrozikiewicz-Rakowska B., Ładyżyński P., Wójcicki J. M., Karnafel W.

Biocybernetics and Biomedical Engineering

|

2014

|

Vol. 34, no. 3

178--183

EN

Background: Patients with diabetic neuropathy exhibit a higher foot temperature than those without neuropathy and they are at risk for foot ulceration. Ambient temperature and foot ulceration additionally influence foot temperature in such patients. The aim of the study was to assess the influence of ambient temperature on foot temperature in patients with an ulcer on one of the feet. Methods: Miniature temperature data loggers were used for the monitoring of foot skin and ambient temperature. Twenty patients with diabetic neuropathy and ten healthy subjects were monitored for about 24 h each. Results: The temperature of the foot with an ulcer correlates significantly with ambient temperature, with the slope of the regression line of 0.09. The temperature of the non-ulcerated foot also correlates significantly with ambient temperature, with the slope of 0.31, however the correlation coefficient and the slope are significantly higher than in the case of the foot with an ulcer. The difference of temperature of the foot with an ulcer and temperature of the foot without an ulcer correlates well with ambient temperature with the slope of _0.219. The temperatures of left and right feet were studied as a function of ambient temperature in healthy individuals and there were no statistically significant differences between correlation coefficients and slopes. Conclusions: It is apparent that ambient temperature influences foot temperature even during foot ulceration. Thus ambient temperature should be taken into consideration in any application when foot temperatures are important, especially in the prediction of diabetic foot ulceration.

4

Novel Dressing Materials Accelerating Wound Healing Made from Dibutyrylchitin

Chilarski A., Szosland L., Krucińska I., Kiekens P., Błasińska A., Schoukens G., Cisło R., Szumilewicz J.

Fibres & Textiles in Eastern Europe

|

2007

|

Vol. 15, no. 4 (63)

77--81

EN

Dibutyrylchitin (DBC), a soluble chitin derivative, is a polymer with confirmed biological properties. DBC was obtained in the reaction of shrimp chitin with butyric anhydride, carried out under heterogeneous condition, in which perchloric acid was used as a catalyst of reaction. Production of DBC batches was carried out on a half - technical scale line. DBC parties were examined by infrared spectrometry, size exclusion chromatography and viscometry. DBC with molar mass of 132×103 daltons was used for the manufacturing of DBC fibres and DBC non-woven materials. DBC non-woven fabrics after γ-sterilisation were applied to a group of nine patients with different indications. DBC dressing materials were used exluding the use of other medical products. Satisfactory results of wound healing were achieved in most cases, especially in cases of burn wounds and postoperative/posttraumatic wounds and various other conditions causing skin/epidermis loss.

PL

Dibutyrylochityna (DBC) jest polimerem, którego korzystny wpływ na organizm żywy wykazano w badaniach biologicznych. Jest rozpuszczalną, estrową pochodną chityny pozyskiwanej z różnorodnych źródeł, stosunkowo łatwą do przetworzenia w procesach technologicznych. Do celów pracy syntezę DBC prowadzono na skale większą od laboratoryjnej, zgodnie z patentem polskim. Z otrzymanego polimeru, o masie molowej 132 kDa, wytworzono włókna a z nich włókniny. Sterylizowane płatki włóknin aplikowano na rany o różnej etiologii bez stosowania dodatkowych leków. W większości przypadków zaobserwowano korzystny wpływ dibutyrylochityny na proces gojenia ran. W żadnym z przypadków nie stwierdzono niekorzystnych zmian.

5

Termografia komputerowa – zastosowanie w diagnostyce gojenia się ran po alloplastyce przepuklin pachwinowych

Kondras M., Peszyński-Drews C., Modzelewski B.

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna

|

2005

|

Vol. 11, nr 1-2

12-14

PL

Termografia jest bezbolesną, nieinwazyjną, łatwą w użyciu metodą pozwalającą monitorowac i zapisywac zmiany ciepłoty w czasie [1]. Zmiany ciepłoty charakterystyczne dla przebiegu moejscowej reakcji zapalnej pozwalają oceni proces gojenia się ran. Zjawisko to towarzyszące gojeniu się ran pooperacyjnych pozwala na wykrycie, nawet bez obecności klinicznych objawów, zaburzeń tego procesu.

EN

Infrared Thermography is painless, non-invasive, simple metod of diagnosis and monitoring temperature modification on time. Chandes of temperature typical for local inflammatory respons syndrom, could evaluate the proess of wound healing. Thermography may detect disturbances of that process even without any other clinical symptoms.

6

Wound Healing Acceleration by a Textile Dressing Containing Dibutyrylchitin and Chitin

Pielka S., Paluch D., Staniszewska-Kuś J., Żywicka B., Solski L., Szosland L., Czarny A., Zaczyńska E.

Fibres & Textiles in Eastern Europe

|

2003

|

Vol. 11, no. 2 (41)

79--84

EN

New textile dressings containing dibutyrylchitin (DBCH) or regenerated chitin (RC) were prepared in the process of coating a trade polypropylene non-woven material with films of DBCH or RC. The dry dressing material contained ca. 40% of DBCH and 30% of RC. The dressings obtained were cut into pieces of 5×5 cm, sterilised by ethylene oxide and then subjected to biological evaluation required for medical devices. The evaluation included cytotoxicity effects, levels of cytokines TNF-α and IFNs, synthesis of nitrogen oxides (NO2/NO3), intracutaneous irritation, and the influence of full thickness skin lesions on the healing process.DBCH and RC caused no cytotoxic effects or primary irritation either in vitro or in vivo, nor did the activity of TNF-α, IFNs or the nitrogen oxide levels increase, and both had a positive influence on the wound healing process. Both dibutyrylchitin and regenerated chitin used for coating trade polypropylene non-woven material can be regarded as valuable dressing materials that accelerate wound healing.

PL

Nowe materiały opatrunkowe zawierające dibutyrylochitynę (DBCH) lub regenerowaną chitynę (RC) otrzymano w procesie powlekania handlowej włókniny PP warstwą DBCH lub RC. Otrzymane suche materiały opatrunkowe zawierały 40% DBCH lub 30% RC. Celem sprawdzenia możliwości ich zastosowania w medycynie materiały te, pocięte na kwadraty o wymiarach 5 x 5 cm i wysterylizowane dwutlenkiem etylenu, poddano badaniom biologicznym takim jak badania: działania cytotoksycznego, poziomu cytokin TNF i IFN, syntezy tlenków azotu N02/N03, śródskórnego działania drażniącego oraz wpływu na gojenie się ubytków skóry pełnej grubości. W wyniku tych badań, przeprowadzonych in vitro i in vivo stwierdzono, że opracowane materiały nie wywołują działania cytotoksycznego i pierwotnego działania drażniącego, nie powodują wzrostu aktywności TNF i INF oraz poziomu tlenków azotu, a ponadto aktywnie wpływają na proces gojenia się ran. Na tej podstawie uważa się, że zarówno dibutyrylochityna jak i regenerowana chityna mogą stanowić bardzo wartościowy materiał opatrunkowy przyśpieszający gojenie się ran.