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New Glycoside Derivatives of 6H-Indolo{2,3-b]quinolines

Badowska-Rosłonek K., Kaczmarek Ł., Ramza J., Godlewska J., Opolski A., Peczyńska-Czach W.

Polish Journal of Chemistry

2005

Vol. 79 / nr 2

369-386

The series of carbohydrate derivatives of 6H-indolo[2,3-b]quinoline was obtained. Carbohydrate units (2-deoxy-D-glucose, 2-deoxy-D-lactose and 2-deoxy-L-rhamnose) were coupled viaa glycosidic bond to a hydroxyl group placed in a side chain at selected positions of indoloquinoline. Increased solubility was noted for all obtained products. Some of them exhibit also increased in vitro cytotoxicity.