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The aim of the study was to evaluate the ability of lactic acid bacteria strains, isolated from the gastrointestinal tract of chickens, to eliminate ochratoxin A (OTA) in vitro and to investigate whether the mechanism of OTA reduction is adsorption or hydrolysis. The probiotic characteristics of the strains, such as their growth performance and synthesis of lactic acid at 42°C, inhibition of Salmonella spp. and Escherichia spp. growth and susceptibility to antibiotics, was also evaluated. Ochratoxin A reductions in MRS broth depended on the tested strain and ranged from 1% to 29%. The level of OTA reduction was higher at 30°C than at 37 and 42°C and there were no significance differences between OTA reduction obtained with live and heat-treated bacteria cells. The evaluation of probiotic characteristics showed that Pediococcus acidilactici KKP 879 was the strain with more potential to develop a probiotic culture for chickens.
EN
In a recent paper “Self-Assembly of Phenylalanine-Based Molecules”, we h ave studied the formation and stability of phenylalanine and diphenylalani ne constructs. In the case of diphenylalanine we observe nanotubes, however, phenylalanin e molecules aggregate in layers of four, not six, molecules. In the preset paper, we extend this previous work and compare the energetics of all experimentally observed structures, s imulated structures, and designed structures, by way of single point Density Functional The ory ( DFT ) calculations. We take a detailed look at water content, pore size and dipole moments inside ou r phenylalaninecontaining tubes and analyze stabilizing factors in the nanostructures.
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