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Assessment of corneal and fatty tissues biomechanical response in dynamic tonometry tests by using inverse models

Jannesari M., Kadkhodaei M., Mosaddegh P., Kasprzak H., Behrouz M. J.

Acta of Bioengineering and Biomechanics

2018

Vol. 20, no. 1

39--48

The assessment of corneal biomechanics is essential for studying ophthalmological operations, such as refractive surgeries, and for more accurate estimation of intraocular pressure. The chief aim of the current study is to characterize corneal and fatty tissues in order to construct a model to predict eye globe behavior during dynamic tonometry tests. Methods: In the present study, images from corneal deformation, acquired from Corvis ST tonometer, were processed. Then, corneal pure displacement and eye globe retraction were calculated. Utilizing inverse finite element method, corneal material properties were calculated in order to predict pure deformation obtained from Corvis ST. Using a similar approach, material parameters of fatty tissue were estimated in order to predict the eye globe retraction. The model used for fatty tissue was considered as corneal boundary condition in a forward finite element model to create a joint model, which could simulate corneal behavior in dynamic tonometry tests. Results: It was shown that an isotropic material model is accurate enough to predict corneal deformation in dynamic tonometry tests. Moreover, effects of IOP on the estimated material properties were investigated. Finally, utilizing the joint model, it was demonstrated that there is strong correlation between corneal stiffness and the biomechanical parameter introduced by Corvis ST. Conclusions: An eye globe model was constructed and characterized by two distinct inverse models for corneal and fatty tissue. This model can be utilized for predicting eye globe behavior during dynamic tonometry tests besides other ophthalmological operations.

Badania wpływu mikroklimatu podziemnego uzdrowiska w kopalni soli w Wieliczce na masę ciała, zawartość tkanki tłuszczowej i gospodarkę lipidową – doniesienie wstępne

Pośpiech S., Barcucha P., Damijan Z., Błaszczyk J., Czapkowicz-Pośpiech R.

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna

2014

Vol. 20, nr 4

204--216

Celem badania była ocena wpływu podziemnego mikroklimatu kopalni soli na masę ciała, zawartość tkanki tłuszczowej i gospodarkę lipidową człowieka. Badanie przeprowadzono w Komorze Solnej „Jezioro Wessel”, znajdującej się 135 metrów pod ziemią, na poziomie trzecim Kopalni Soli w Wieliczce. Badaniem objęto 43 zdrowe dorosłe osoby. Każdego dnia pobytu dwukrotnie wykonywano pomiar masy ciała oraz zawartości tkanki tłuszczowej. Pomiary prowadzono 15 minut po dotarciu badanych do Komory Solnej i drugi raz 15 minut przed wyjazdem z kopalni. Przed rozpoczęciem badań i po ich zakończeniu uczestnikom pobrano krew obwodową z żyły łokciowej do analiz biochemicznych, obejmujących oznaczenie: cholesterolu całkowitego, cholesterolu HDL i trójglicerydów. Wykonane analizy wskazują, że 14-dniowe, 6,5-godzinne przebywanie w podziemnej atmosferze kopalni soli powoduje istotny statystycznie wzrost masy ciała, wzrost zawartości tkanki tłuszczowej, wzrost cholesterolu HDL i trójglicerydów oraz nieistotny statystycznie spadek poziomu cholesterolu całkowitego.

The aim of this research was to evaluate the influence of the underground microclimate salt mine on the body mass, fatty tissue content and lipid balance. The research was performed in the Lake Wessel Chamber, situated 135 meters under the ground, on the 3rd level of Wieliczka salt mine. The studied group comprised of 43 healthy adult people. Each day of the stay in the salt chamber the body weight and fatty tissue content were measured. Before the examination and after it, the peripheral blood samples from elbow veins of the subjects were taken for further study. The blood tests included: the total cholesterol, high density lipoproteins (HDL) and triglycerides. Statistical analysis revealed that 14-day, 6,5-hour long exposure to the underground atmosphere caused a statistically significant increase: of the body weight, fatty tissue content and of the HDL. Statistically insignificant decrease of the total cholesterol and triglycerides was also observed.

The effect of the fatty tissue on EMG signal in young women

Bartuzi P., Tokarski T., Roman-Liu D.

Acta of Bioengineering and Biomechanics

2010

Vol. 12, no. 2

87-92

The aim of this study was to investigate the influence of fatty tissue layer on EMG signal parameters as a function of force level and type of muscle in young women. On the basis of body mass index (BMI) and the amount of fatty tissue (FT) 30 young women were divided into two equal groups: obese (O) and reference group (R). The EMG signal was measured on 5 levels of load from 2 muscles: palmaris longus (PL) and rectus abdominis (RA). The EMG signal parameters (RMS and MPF) were analysed. The results of the study suggest that the EMG signal is sensitive to fatty tissue layer. However, the influence of fatty tissue layer on the EMG signal is dependent on the muscle examined. The analysis of the dependence of the EMG signal on fatty tissue layer based on more detailed parameters of the power spectrum is desirable.