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Solubility parameter and its components calculated by IGC method

Adamska K., Voelkel A.

Polish Journal of Chemical Technology

2006

Vol. 8, nr 2

86-89

Inverse gas chromatography (IGC) method has been applied for the estimation of the solubility parameter for pharmaceutical excipients and polyethylene glycols. Experimental values of the Flory-Huggins interaction parameter between material and test solutes were used to determine the solubility parameters according to Guillet and his co-workers' procedure. Hansen solubility parameters (HSP) were calculated using Voelkel and Janas's concept for estimating the components of a corrected solubility parameter.