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Role and applications of circulatory models in cardiovascular pathophysiology

Ferrari G., Kozarski M., De Lazzari C., Górczyńska K., Pałko K. J., Zieliński K., Di Molfetta A., Darowski M.

Biocybernetics and Biomedical Engineering

2009

Vol. 29, no. 4

3-24

Circulatory models are relevant for research, education and testing of prosthetic devices/components. Independently of its structure that can be numerical, physical or hybrid the models can be used in different areas of cardiovascular pathophysiology. However, the models are often used to reproduce specific circulatory conditions instead of being used as 'systemic' tools. That is to say, the models are used to evaluate the global effects of external disturbances such as pathologies, therapies, special environments or surgery on the circulatory system. Aim of this paper is to illustrate a family of circulatory models developed to represent the whole circulatory system in pathophysiological conditions describing some of the possible applications.

Physical modelling of the cardiovascular system : development of a new simulation system based on hybrid (numerical-hydraulic) components

Ferrari G., De Lazzari C., Kozarski M., Clemente F., Górczyńska K., Mimmo R., Tosti G., Guaragno M.

Biocybernetics and Biomedical Engineering

2003

Vol. 23, no. 2

3-15

Research, education, testing of assist devices and training are among the applications of physical models of the circulation. Unfortunately, they are rather expensive and the scope of their use is structure-dependent as it is not easy to modify them. As numerical models do not have these limitations, our aim is to develop a physical model of the circulation limited to the sections of interest merging them with numerical models representing the remaining parts of the circulatory system. The system under development is therefore a hybrid where physical and numerical sections, merged together, represent the circulatory system. The sections developed till now represent one of the ventricles and part of the arterial tree. This paper is devoted to the description of the hybrid ventricular model and its first applications.