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Evaluation of the new polyurethanes capillary membrane for cell immunoisolation. Results from in vitro studies

Resiak I., Wojciechowski C.

Biocybernetics and Biomedical Engineering

2004

Vol. 24, no. 2

69-79

Highly biocompatible and mechanically resistant semipermeable membranes are required for macroencapsulation of cells or tissues. For this purpose two series of aromatic as well as aliphatic polyurethanes were elaborated for the production of hollow fibre membranes by the phase inversion method and the wet spinning technique. The influence of the polyurethane structure, i.e. type of the hard segments and content of the soft segments on the membrane morphology and its transport properties were investigated.