Wyniki wyszukiwania - BazTech

Ograniczanie wyników

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: diastereomers

Sortuj według:

Ogranicz wyniki do:

An Approach to Asymmetric Synthesis of New Pyridine Aminophosphine Oxides. Preparation of the Diastereomerically Pure 1-(Pyridine-3-yl)-1-[N-(alfa- methyl benzyl amino)]-methyl-diphenylphosphine Oxides and 1-(Pyridine-3-yl)-1-[N-(alfa-methylbenzylamino)]

Guzik M., Olszewski T. K., Boduszek B.

Polish Journal of Chemistry

2007

Vol. 81, nr 11

1879-1885

A series of diastereomerically pure aminophosphine oxides derived from pyridine- 3-carboxaldehyde and chiral amine was synthesized. The aminophosphine oxides were obtained by an addition reaction of the diphenylphosphine oxide or racemic t-butylphenylphosphine oxide to the optically active, corresponding chiral aldimines, which were obtained from pyridine-3-carboxaldehyde and enantiomers of alfa-methyl benzyl - amine. The formed diastereomers were easy separated by crystallization from acetone.

Physical image vs. structure relation, 4[1]. Configuration and conformation determination of some bicyclic lactams by 1H NMR and theoretical methods

Nazarski R. B., Leśniak S.

Bulletin of the Polish Academy of Sciences. Chemistry

2000

Vol. 48, No. 1

17-25

Resolution-enhanced H NMR spectra of six single diastereomers of fused-ring sulfur-containing lactams have been recorded and interpreted. In joint analysis of derived couplings Ť/HH> performed with use of the Karplus-Conroy type relationship and results of static MM calculations, it was possible to determine the configuration of title compounds and the conformation elucidation of their six-membered rings. Simultaneously, the stereochemistry of the observed ring-closure reaction was determined. The application of TNDO/2 method for the prediction of n JHH values is also briefly discussed.