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Configurational forces for growth and shape regulations in morphogenesis

Charletta P., Ambrosi D., Maugin G.

Bulletin of the Polish Academy of Sciences. Technical Sciences

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2012

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Vol. 60, nr 2

253-257

EN

Morphogenetic theories investigate the mechanisms of creation and regulation of definite biological forms in living organisms. The incredible diversity of shapes and sizes is generated through a barely unknown coordination of biochemical processes occurring at molecular levels. Such a crosstalk not only defines the rules of a robust scheme of matter differentiation, but it also has the capacity to adapt with respect to some variations of the environmental conditions. In this work, we propose a continuum model of growth and mass transport for biological materials during morphogenetic processes. Using the theory of configurational forces, we define the thermomechanical bases for understanding how both the mechanical and the biochemical states can orchestrate growth. The model is successfully applied to describe the morphogen-driven growth control in the imaginal wing disc of Drosophila melanogaster.

2

Non-isothermal phase-field models and evolution equation

Morro A.

Archives of Mechanics

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2006

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Vol. 58, nr 3

257-271

EN

Phase transitions between two phases are modelled as space regions where a phase field, or order parameter, changes smoothly. The literature shows a seeming contradiction in that some papers lead to the use of the reduced chemical potential through the temperature, others do not. The paper has a threefold purpose. First, to revise the arguments of known approaches and possibly generalize the associated schemes. Secondly, to show that a further approach is possible which involves the phase field as an internal variable. Thirdly, to contrast the various schemes and the corresponding results. It follows that differences arise because different fields enter the models and different forms are considered for the balance of energy and the second law of thermodynamics.

3

On nonlocal gradient model of inelastic heterogeneous media

Stumpf H., Saczuk J

Journal of Theoretical and Applied Mechanics

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2002

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Vol. 40 nr 1

205-234

EN

The aim of this paper is to investigate the influence of nonlocality on the physical and material field equations of heterogeneous media. Taking into account that plastic deformations in metals or damage in brittle and ductile materials are governed by physical mechanisms observed on levels with different lengthscales, we introduce a 6-dimensional kinematical concept with two locally defined vectors to model the material behaviour on a macro- and meso- or microlevel. Using a variational procedure the physical and material balance laws, boundary and transversality conditions are derived for macrp- and microdeformations of heterogeneous media. The disspation inquality including relaxation terms for transport processes is presented. The constitutive equations are formulated with macro- and microstrain measures, their gradients and time rates, and the anisotropy tensor as arguments, where the latter can be considered as a coupling measure between the deformed macrostates with compatible microstates. The model presented in this paper delivers a framework, which enables one to derive various nonlocal and gradient theories by introducing simplifying assumptions. As the special case a solid-void model is considered.

PL

Celem pracy jest zbadanie wpływu nielokalności na fizyczne i materialne równania pola ośrodków heterogenicznych. Biorąc pod uwagę, że plastyczna deformacja w metalach lub zniszczenie w kruchych i ciągliwych materiałach rządzone są przez fizyczne mechanizmy na różnych poziomach skali, wprowadzono 6-wymiarową strukturę z dwoma lokalnie zdefiniowanymi wektorami do modelowania materialnego zachowania ośrodka na poziomie makro- i mezo- lub mikroskali. Wykorzystując wariacyjną procedurę otrzymano fizyczne i materialne prawa bilansu, warunki brzegowe i transwersalność dla makro- i mikrodeformacji ośrodków heterogenicznych. Przedstawiona nierówność dyssypacyjna zawiera człony relaksacyjne procesów transportu. Sformułowane równania konstytutywne wyrażono przy pomocy miar makro- i mikroodkształcenia, ich gradientów i przyrostów oraz tensora anizotropii, gdzie ostatni argument może być traktowany jako miara sprzężenia pomiędzy odkształconymi makrostanami i kompatybilnymi mikrostanami. Przedstawiony w pracy model dostarcza podstaw, które poprzez wprowadzenie uproszczających założeń umożliwiają otrzymanie różnych postaci nielokalnych i gradientowych teorii. Jako przypadek szczególny rozpatrzono model typu ciało stałe-pustka.