Wyniki wyszukiwania - BazTech

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Collagen - structure, properties and application

Owczarzy Aleksandra, Kurasiński Robert, Kulig Karolina, Rogóż Wojciech, Szkudlarek Agnieszka, Maciążek-Jurczyk Małgorzata

Engineering of Biomaterials

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2020

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Vol. 23, no. 156

17--23

EN

Collagen is the dominant component of the extracellular matrix of mammals. It occurs almost in all animal tissues. Collagen is a highly heterogeneous protein. The collagen protein family is characterized by great diversity in terms of structure, occurrence, and function. Up till now, 29 types of collagens proteins have been classified. The representation of individual types of collagen has certain common features. The most important property is the above-average mechanical strength that results directly from the spatial structure. Collagen is a building material for most tissues and organs. It also plays an important role in the process of cell growth and differentiation, which results from the specific structure of collagen fibers as well as their ability to adhere. The development of research techniques allowed to study in detail the molecular structure and properties of collagen. Therefore, collagen has become a subject of interest in many branches of science. Synthetic recombinant collagen fibers were developed as the basis of collagen biomaterials for medical applications, including implantology or gynecology. The specific structure of collagen also makes it applicable as a protein carrier in drug delivery systems (DDS), particularly in the treatment of cancer and genetic diseases. The use of tissue regenerative abilities and an interdisciplinary look at the properties of collagen and collagen-based biomaterials may constitute the future of medical development.

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Nanofibrous membrane with fibrin and collagen structures as carriers for skin cells

Bacakova M., Riedel T., Stranska D., Brynda E., Bacakova L.

Engineering of Biomaterials

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2014

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Vol. 17, no. 128-129

2--4

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Viscoelastic properties of the papillary muscle: experimental and theoretical study

Smoluk L., Protsenko Y.

Acta of Bioengineering and Biomechanics

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2012

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Vol. 14, no. 4

37-44

EN

It is well known that the structure of biological tissue is closely related to tissue functions and defines its viscoelastic properties. It is necessary to create a model combining structural organization of myocardium and its viscoelastic properties to develop a model of cardiac wall of intact or deceased heart. This paper is devoted to experimental and theoretical study of viscoelastic behavior of isolated myocardial samples. A three-dimensional structural-functional model of papillary muscle is presented. The model adequately describes nonlinear viscoelastic behavior of isolated papillary muscles under uniaxial strain both in static condition and under dynamic loading.

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Structural cohesion within anulus fibrosus: 'live' optical and micromechanical studies

Pezowicz C., Robertson P., Broom N.

Zeszyty Naukowe Katedry Mechaniki Stosowanej / Politechnika Śląska

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2006

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z. 26

281-284

EN

The purpose of this study was to use simultaneous micro-tensile and Nomarski DIG optical imaging of 'live' sections of the disc annulus to investigate the fundamental structural mechanisms that create cohesion within and between lamellae.