The cochlear microphonic (CM) is an electrical signal generated inside the cochlea in response to sound. This electrical signal reflects mechanical activity in the cochlea and the excitation processes involved in its generation. However, the difficulty of obtaining this signal and the simplicity of obtaining other signals such as otoacoustic emissions have discouraged the use of the cochlear microphonic as a tool for studying cochlear functions. In this article, a model of the cochlea is presented which integrates both mechanical and electrical aspects, enabling the interaction between them to be investigated. The resulting model is then used to observe the effect of the cochlear amplifier on the CM. The results indicate that while the cochlear amplifier significantly amplifies the basilar membrane displacement, the effect on the CM is less significant. Both of these outcomes are consistent with previous physiological findings. Moreover, the close match between mechanical and electrical predictions of the model and experimental measurements validates the model, and suggests that further investiga- tions using the model into various pathologies and anomalies are warranted.
2
Dostęp do pełnego tekstu na zewnętrznej witrynie WWW
The aim of the experiment was to examine the effect of noise and mechanical vibrations generated during the drilling of the bones surrounding the cochlea on the cochlear microphonics (CM). The experiment was carried out on a group of 40 guinea pigs divided equally into a group to be studied and a control group. In the studied group, CM values were measured three times: immediately after opening the bulla, after 30 minutes of nonstop drilling and two hours later, whereas in the control group they were measured twice: immediately after opening the bulla and 2.5 hours later. In this way the post-drilling shock and the long-term injuries to the cochlea could be studied. A statistical analysis of the obtained results shows that surgical drilling may cause an average decrease of 50-60% in CM values in comparison with the control group.
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.