W artykule przedstawiono charakterystykę kawy jako surowca oraz przebieg procesu technologicznego otrzymywania kawy prażonej. Omówiono najważniejsze składniki bioaktywne kawy tj. polifenole, kofeinę, trygonelinę, cholinę, diterpeny, substancje drażniące. Przedyskutowano wpływ kawy na zdrowie człowieka i stwierdzono, że jest napojem bezpiecznym, wykazującym cechy prozdrowotne, gdy spożywana jest przez osoby dorosłe w umiarkowanych ilościach.
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The main features of coffee as a raw material and its bioactive ingredients, such as polyphenols, caffeine, trigonelline, choline, diterpenes, and irritants are presented. The pipeline of the technological process of obtaining roasted coffee and its impact on human health was presented and discussed as well. Coffee has been recognized as a safe and health-promoting drink when consumed in moderate amounts by adults.
CDPcholine (citicoline, CDPCho) shows beneficial effects in various Central Nervous System (CNS) injury models and neurodegenerative diseases. Previous studies demonstrate conflictingMagnetic Resonance Spectroscopy (MRS) reports regarding the impact of different choline-containing compounds and its doses on brain metabolites. This preliminary study was designed to evaluate concentration changes of brain MR-visible metabolites following intravenous CDPCholine. Twelve healthy rats treated with CDPCholine in three subsequent doses of 1gram/kg eachwere examined using 1Hand 31P MRS in vivo. Following intravenous CDPCholine administration there was a statistically significant increase of the Cho/Cr ratio after first CDPCholine injection. The evidence of CDPcholine influence on brain metabolites has been shown.
CDPcholine (citicoline, CDPCho) shows beneficial effects in various Central Nervous System (CNS) injury models and neurodegenerative diseases. Previous studies demonstrate conflictingMagnetic Resonance Spectroscopy (MRS) reports regarding the impact of different choline-containing compounds and its doses on brain metabolites. This preliminary study was designed to evaluate concentration changes of brain MR-visible metabolites following intravenous CDPCholine. Twelve healthy rats treated with CDPCholine in three subsequent doses of 1gram/kg eachwere examined using 1Hand 31P MRS in vivo. Following intravenous CDPCholine administration there was a statistically significant increase of the Cho/Cr ratio after first CDPCholine injection. The evidence of CDPcholine influence on brain metabolites has been shown.
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