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1 Journal of Achievements in Materials and Manufacturing Engineering

1 2010

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Follow up of biocompatibity of new total hip joint endoprosthesis in a canine model

Rehak L'., Zitnansky M., Soltes I., Horecky J.

Journal of Achievements in Materials and Manufacturing Engineering

2010

Vol. 43, nr 1

260-263

Purpose: of this paper was the follow up of biologic compatibility and functional use of new type endoprosthesis in a canine model. Design/methodology/approach: Prospective animal study with evaluation of new type ZRM of titanium alloy cementless total hip replacement (THR) in dogs in 2007. We used congruent ceramic head and polyethylene acetabular inlay. That is the gold standard in THR. The methods of X ray imaging evaluation after implantation and overgrowth evaluation were employed. We evaluated loading and use of the leg during walking and running. Total hip joint replacements were implanted in 6 dogs – German Shepards under general anesthesia. The follow up time was 6 months. We compared X ray findings after the operation and after 6 months, wound healing, use of THR during leg loading and biocompatibility of THR in femur and pelvis. Findings: The femoral and acetabular components were anchored using a press-fit technique. We found good biocompatibility in 5 dogs with good loading during walking and running, one complication with femoral fracture and wound abscess. At six months, there was good bony ongrowth of the THR in 5 dogs and small overgrowth on the surface of THR in one dog, deemed as complication. In the same animal, explanation of the THR was performed, due to fracture. Research limitations/implications: This study was not monitored. In the future, we would like to perform a randomized study design with a control group. Practical implications: The new THR developed by authors can restore function in canine model of damaged hip joint. The press fit anchorage of the cup allowed firm adhesion of the cup surface to the pelvic bone and likewise, the femoral component demonstrated firm fixation in the proximal femur. Originality/value: This paper is original by presenting the first results of new THR in canine model. The value of this paper is in laying groundwork for human study in the future.