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Design and fabrication of 125I seeds for brachytherapy using capillary-based microfluidic technique

Wang Yuan, Zhang Miao, Song Tong, Chang Zhenqi

Nukleonika

2021

Vol. 66, No. 2

55--60

A new kind of 125I seeds with a core-shell structure were synthesized by an easy assembling–disassembling coaxial capillaries microfluidic device. The dose distribution of a 125I brachytherapy source fabricated by arranging six 125I seeds collinearly within a cylindrical titanium capsule was simulated by modelling the source in a water phantom using Monte Carlo N-Particle Transport code. The infl uence of the motion and the core size of the 125I seeds on the dose distribution was also studied in this work.