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Selected applications of near infrared optical methods in medical diagnosis

Maniewski R., Liebert A., Kacprzak M., Zbieć A.

Opto-Electronics Review

2004

Vol. 12, No. 3

255-262

Optical methods from the near infrared range, in particular the laser-Doppler flowmetry and the near infrared spectroscopy offer a new non-invasive, real-time technique for monitoring of the blood perfusion and oxygenation in a living tissue. In spite of some instrumental problems, e.g., relative calibration and unknown sampling measurement depth, these methods have been already used in clinical studies. In this paper, the principle of the methods and instrumentation have been described. The advantages and limitations of these techniques are also discussed and new trends in technical development of the laser-Doppler flowmetry and the near infrared spectroscopy, especially contactless perfusion scanning and photons time of flight measurement, have been shown. Finally, selected clinical applications of all presented methods have been described.

Optical methods for tissue perfusion and oxygenation measurements

Maniewski R., Liebert A.

Biocybernetics and Biomedical Engineering

2002

Vol. 22, no. 2-3

99-112

Optical methods from the infrared range, especially Laser-Doppler flowmetry and near infrared spectroscopy offer a new non-invasive, real-time technique for monitoring of blood perfusion and oxygenation in living tissue. In spite of some instrumental problems e.g. relative calibration, unknown sampling measurement depth, these methods are already used in clinical studies. In the paper the methods principle, technical development and selected clinical applications have been described.

Laser-Doppler measurements of microvascular perfusion

Maniewski R., Libert A.

Biocybernetics and Biomedical Engineering

1998

Vol. 18, no. 1-2

49-57

Laser-DoppIer method offers a new non-invasive, reaI-time technique for monitoring of bIood perfusion in microcirculation. In spite of some instrumental problems e.g. reIative calibration, unknown sampling measurement depth, the method is wideIy used in clinical experiments. In the paper the method principle, technical development of the laser-Doppler instruments and selected clinical appIications have been described.

Metoda laserowo-dopplerowska jest nową nieinwazyjną techniką monitorowania w czasie rzeczywistym ukrwienia w systemie mikronaczyniowym. Pomimo pewnych ograniczeń instrumentalnych, jak: kalibracja w jednostkach względnych i niedokładnie znana objętość mierzonej tkanki, metoda ta znalazła już wiele zastosowań w badaniach klinicznych. W pracy omówiono podstawy metody oraz technikę pomiaru i aparaturę laserowo-dopplerowską do pomiaru mikroukrwienia a także przedstawiono wybrane zastosowania, w tym wyniki badań własnych.