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The method of evaluation of the abilities of the lining soft materials to relieve the mucous membran

Chladek G., Żmudzki J., Malara P.

Archives of Materials Science and Engineering

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2013

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Vol. 64, nr 2

125--134

EN

Purpose: The presentation of a simple method of evaluation of the effectiveness to relieve the mucous membrane under thednture through soft lining materials, which is based on the analysis of creep curves and energy dissipated by the samples during the cyclic compression. Design/methodology/approach: On the testing machine there were conducted studies of time characteristics and there was determined the energy dissipated by the samples during the cyclic compression. The results were subjected to the analysis of variation ANOVA (α=0.05) with the Newman-Keuls post-hoc test. Findings: The presented method allowed to conduct the evaluation of abilities to relieve the mucous membrane of soft lining materials significantly different in hardness. The studies showed that the softer materials characterised with a greater ability to dissipate energy, nevertheless, after taking the load off, the return to the original form in case of materials with the lowest hardness lasted much longer. The samples of softer materials with large values of stress underwent much greater stiffening, Research limitations/implications: Limitations not allow the full translation of the obtained results into the expected results of clinical trials. The demonstrated relations between the behaviour of the samples and the hardness of materials are proper for the tested materials, but not necessarily for other materials of a similar hardness. Practical implications: The presented methodology of the research is even closer to the expected clinical reality, when the alveolar ridge is more uniform and flat, but in order to obtain an even fuller image of the situation in case of uneven or sharp alveolar ridges, one should conduct additional tests with the method consisting of the load of the samples with a properly shaped penetrator. Originality/value: The advantages of the presented methods are: the possibility for a quantitative use of the comparison of energy dissipated by the samples and the estimation of the material reaction while maintaining the possibility to use the tests of variable values of stresses, what enables an easy association of the obtained results with the values of stresses, which cause pain sensations in the mucous.

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New egzoluminal circular surgical stapler

Drop R., Mazurkiewicz S., Woźny Z., Majcher P., Tabor A.

Acta of Bioengineering and Biomechanics

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2010

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Vol. 12, no. 3

113-117

EN

The study presents the design, prototype version and preliminary results of in vivo testing of the egzoluminal circular surgical stapler for “end-to-end” anastomosis of bowels after the resection, where staples are put outside the intestinal lumen, and walls of the intestinal tube directly contact the intestinal mucous membrane. The adopted idea of an “end-to-end” intestinal anastomosis as well as a strong need for a device that would be re-usable have determined its specific design. The device is characterised by a kinematic mode of operation, different from the operating mode of commonly used staplers, and hence by a specific combination of the individual components. The in vivo tests, successfully conducted on animals, have proved that this method of anastomosis as well as the device used for its practical performance are fully applicable in clinical practice, as best shown by patent application No. P 386369.

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Evaluation method of saliva and oral cavity mucous membrane in the aspect of holding a denture on an atrophic base

Chladek W., Lipski T., Kasperski J.

Acta of Bioengineering and Biomechanics

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2007

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Vol. 9, nr 1

53-60

EN

The paper presents application of the authors’ own method of investigating the secretion and elasticity of saliva as well as resilience of mucous membrane in evaluation of force holding the lower denture in the base. The object of research is a complete mucus lower denture cooperating with the base with a tooth-caving that is on the decline. Results of the tests of a horizontal force knocking the denture off the base were assumed as objective effectiveness evaluation criteria. Clinical investigation has been carried out in a group of 126 patients using diagnostic devices constructed according to the authors’ own conception. The elasticity of saliva was determined by measuring the length up to the break point where saliva loses elasticity, the sample volume being 55.26 mm3. The amount of saliva was determined on the basis of the area on which saliva remains and that is created by pressing the saliva with a force of 140 N by means of a 0.22 mm thick circular filter paper with a diameter of 8 mm. The filtering paper had earlier been put for 30 seconds on a mucous membrane in the area of molars. The resilience was determined on the basis of the penetrator’s cavity dented by a force of 1 N into the mucous membrane. Results obtained during the examination of a group of patients enabled an unambiguous numerical description of the characteristic features of oral cavity environment. A statistically significant influence of all investigated factors on the force necessary to knock the denture off the base has been determined. A significance hierarchy of the factors investigated as well as the ranges of variability in the parameters measured have been defined. The resilience of the mucous membrane has affected the denture knocking off force the most. It had a value of 0.4 mm up to 2.1 mm during an impact of a pointwise pressure of an average value of 0.99 mm. Then, the influence of the amount of the secreted saliva has been observed. The amount of the saliva gathered on the filter paper was expressed in terms of a “flood” area obtained after pressing the paper and amounted to 180 mm2 up to 660 mm2, with the average of 468.75 mm2. The least important factor was the elasticity determined by the break length of a saliva sample. The lengths of breakpoints measured were from 4.8 mm for saliva with a dominant serum secretion content up to 24.1 mm for saliva with a dominant mucus secretion content. The average value for the whole population examined was estimated at 14.19 mm.

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Transport leku przez błonę śluzową policzka

Mościcka A., Ciach T.

Inżynieria i Aparatura Chemiczna

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2006

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Nr 5s

100-101

EN

The paper presented shows that iontophoresis enhances drug-transport via buccal mucosa. In the experimental study a two-chamber permeation cell with silver electrodes was designed to carry out in vitro iontophoresis. Naltrexone hydrochlori-de was used as a model drug. A considerable increase of the mass transfer rate was observed for current density equal to l m A/cm2.